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    RPL42B ribosomal 60S subunit protein L42B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856544, updated on 13-Apr-2024

    Summary

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    Gene symbol
    RPL42B
    Gene description
    ribosomal 60S subunit protein L42B
    Primary source
    SGD:S000001183
    Locus tag
    YHR141C
    See related
    AllianceGenome:SGD:S000001183
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MAK18
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Orthologous to several human genes including RPL36AL (ribosomal protein L36a like). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RPL42B in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    2
    Sequence:
    Chromosome: VIII; NC_001140.6 (381990..382751, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Chs7p Neighboring gene Dse2p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Translation and M1 double-stranded RNA propagation: MAK18 = RPL41B and cycloheximide curing. Carroll K, et al. J Bacteriol, 1995 May. PMID 7751301, Free PMC Article
    2. Drastic alteration of cycloheximide sensitivity by substitution of one amino acid in the L41 ribosomal protein of yeasts. Kawai S, et al. J Bacteriol, 1992 Jan. PMID 1729213, Free PMC Article
    3. Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome. Pellegrino S, et al. Nucleic Acids Res, 2019 Apr 8. PMID 30759226, Free PMC Article
    4. The primary structure of protein 44 from the large subunit of yeast ribosomes. Itoh T, et al. FEBS Lett, 1978 Dec 15. PMID 365584
    5. Molecular characterization of chromosomal genes affecting double-stranded RNA replication in Saccharomyces cerevisiae. Icho T, et al. Basic Life Sci, 1986. PMID 3551912

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IC
    Inferred by Curator
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in response to antibiotic IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to cycloheximide IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L42B
    NP_012010.1
    • Ribosomal 60S subunit protein L42B; required for propagation of the killer toxin-encoding M1 double-stranded RNA satellite of the L-A double-stranded RNA virus; homologous to mammalian ribosomal protein L36A, no bacterial homolog; RPL42B has a paralog, RPL42A, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      381990..382751 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179271.1 → NP_012010.1  TPA: ribosomal 60S subunit protein L42B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012010.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DL90, P02405, P0CX27, P0CX28
      UniProtKB/TrEMBL
      A6ZRS2, B3LP17, C8Z9T8, G2WFL4, N1P172
      Conserved Domains (1) summary
      PTZ00157
      Location:1 → 86
      PTZ00157; 60S ribosomal protein L36a; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    4V88_Bo.1
    4V88_Do.1
    4V8T_o.1
    5APN_o.1
    5APO_o.1
    5H4P_o.1
    5T62_Q.1
    5T6R_Q.1
    6N8J_q.1
    6N8K_q.1
    6N8L_q.1
    6N8M_Q.1
    6N8N_Q.1
    6N8O_Q.1
    7AZY_Q.1
    P0CX27.1
    P0CX28.1

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