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    BUB3.2 Transducin/WD40 repeat-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841414, updated on 7-Sep-2023

    Summary

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    Gene symbol
    BUB3.2
    Gene description
    Transducin/WD40 repeat-like superfamily protein
    Primary source
    Araport:AT1G49910
    Locus tag
    AT1G49910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    BUB (BUDDING UNINHIBITED BY BENZYMIDAZOL) 3.2; T18C15.2; T18C15_2
    Summary
    Encodes a homolog of the yeast and human BUB3 (BUDDING UNINHIBITED BY BENZYMIDAZOL 3) protein. Yeast and human BUB3s function in spindle assembly checkpoint control.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    9
    Sequence:
    Chromosome: 1; NC_003070.9 (18478951..18481539)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene QWRF motif protein (DUF566) Neighboring gene C2H2 type zinc finger transcription factor family Neighboring gene MuDR family transposase Neighboring gene alanine-tRNA ligase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of the BUB3 protein in phragmoplast microtubule reorganization during cytokinesis. Zhang H, et al. Nat Plants, 2018 Jul. PMID 29967519
    2. Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes. Zhang Y, et al. Plant Cell, 2008 Jun. PMID 18552200, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. role in phragmoplast microtubule reorganization during cytokinesis
      Title: Role of the BUB3 protein in phragmoplast microtubule reorganization during cytokinesis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_103878.2

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Transducin/WD40 repeat-like superfamily protein
    NP_175413.1
    • BUB (BUDDING UNINHIBITED BY BENZYMIDAZOL) 3.2 (BUB3.2); CONTAINS InterPro DOMAIN/s: WD40 repeat-like-containing domain (InterPro:IPR011046), WD40 repeat 2 (InterPro:IPR019782), WD40-repeat-containing domain (InterPro:IPR017986), WD40 repeat (InterPro:IPR001680), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781), G-protein beta WD-40 repeat, region (InterPro:IPR020472); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT3G19590.1); Has 8710 Blast hits to 6264 proteins in 448 species: Archae - 22; Bacteria - 1987; Metazoa - 2791; Fungi - 2014; Plants - 703; Viruses - 0; Other Eukaryotes - 1193 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      18478951..18481539
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103878.2 → NP_175413.1  Transducin/WD40 repeat-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175413.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C6C4, Q9C701
      UniProtKB/TrEMBL
      A0A178W7L6, A0A5S9WN36, A0A7G2E028
      Conserved Domains (2) summary
      sd00039
      Location:19 → 55
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:16 → 302
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C701.1

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