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    CYP714A1 cytochrome P450, family 714, subfamily A, polypeptide 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832560, updated on 15-Feb-2024

    Summary

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    Gene symbol
    CYP714A1
    Gene description
    cytochrome P450, family 714, subfamily A, polypeptide 1
    Primary source
    Araport:AT5G24910
    Locus tag
    AT5G24910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cytochrome P450; ELA1; EUI-like p450 A1; F6A4.120; F6A4_120; family 714; polypeptide 1; subfamily A
    Summary
    Member of CYP714A. Encodes one of the two tandemly duplicated gene pair ELA1 (CYP714A1) and ELA2 (CYP714A2), homologs of the rice cytochrome P450 monooxygenase gene EUI1. Double mutation of ELA1 and ELA2 results in increased biomass and enlarged organs.
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (8567504..8570367, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene stress response NST1-like protein Neighboring gene cytochrome P450, family 714, subfamily A, polypeptide 2 Neighboring gene pseudo Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of Arabidopsis CYP714A1 and CYP714A2 reveals that they are distinct gibberellin modification enzymes. Nomura T, et al. Plant Cell Physiol, 2013 Nov. PMID 24009336
    2. Two Arabidopsis cytochrome P450 monooxygenases, CYP714A1 and CYP714A2, function redundantly in plant development through gibberellin deactivation. Zhang Y, et al. Plant J, 2011 Jul. PMID 21457373
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714
    4. Multi-omics network-based functional annotation of unknown Arabidopsis genes. Depuydt T, et al. Plant J, 2021 Nov. PMID 34562334

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CYP714 family proteins contribute to the production of diverse gibberellin compounds through various oxidations of C and D rings in both monocots and eudicots.
      Title: Functional analysis of Arabidopsis CYP714A1 and CYP714A2 reveals that they are distinct gibberellin modification enzymes.
    2. CYP714A1 and CYP714A2 function redundantly in regulating plant growth and development, most likely through mediating gibberellin catabolism.
      Title: Two Arabidopsis cytochrome P450 monooxygenases, CYP714A1 and CYP714A2, function redundantly in plant development through gibberellin deactivation.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_001343904.1
    NM_122400.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450, family 714, subfamily A, polypeptide 1
    NP_568463.1
    • ''cytochrome P450, family 714, subfamily A, polypeptide 1'' (CYP714A1); FUNCTIONS IN: electron carrier activity, monooxygenase activity, iron ion binding, oxygen binding, heme binding; INVOLVED IN: oxidation reduction; LOCATED IN: endomembrane system; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 714, subfamily A, polypeptide 2 (TAIR:AT5G24900.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      8567504..8570367 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122400.3 → NP_568463.1  cytochrome P450, family 714, subfamily A, polypeptide 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568463.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93Z79
      UniProtKB/TrEMBL
      A0A178UEV5, A0A5S9Y844, A0A654G4F3
      Conserved Domains (1) summary
      cd20640
      Location:91 → 527
      CYP714; cytochrome P450 family 714

    2. NM_001343904.1 → NP_001332750.1  cytochrome P450, family 714, subfamily A, polypeptide 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1R7T3K0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93Z79.1

    Gene LinkOut

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