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    TPR1 Tetratricopeptide repeat (TPR)-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829171, updated on 15-Oct-2023

    Summary

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    Gene symbol
    TPR1
    Gene description
    Tetratricopeptide repeat (TPR)-like superfamily protein
    Primary source
    Araport:AT4G30480
    Locus tag
    AT4G30480
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtTPR1; F17I23.180; F17I23_180; tetratricopeptide repeat 1
    Summary
    Encodes one of the 36 carboxylate clamp (CC)-tetratricopeptide repeat (TPR) proteins (Prasad 2010, Pubmed ID: 20856808). Interacts with Hsp90/Hsp70 as co-chaperone.
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    Genomic context

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    See TPR1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (14897346..14899121)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene glycine-rich protein Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene AFG1-like ATPase family protein Neighboring gene transmembrane protein (DUF788) Neighboring gene autophagy 18 B-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In silico identification of carboxylate clamp type tetratricopeptide repeat proteins in Arabidopsis and rice as putative co-chaperones of Hsp90/Hsp70. Prasad BD, et al. PLoS One, 2010 Sep 15. PMID 20856808, Free PMC Article
    2. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001036679.1
    NM_119194.5
    NM_179226.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables Hsp90 protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Tetratricopeptide repeat (TPR)-like superfamily protein
    NP_001031756.1
    • Tetratricopeptide repeat (TPR)-like superfamily protein; FUNCTIONS IN: binding; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide-like helical (InterPro:IPR011990); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_194777.3
    • Tetratricopeptide repeat (TPR)-like superfamily protein; FUNCTIONS IN: binding; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: tetratricopetide-repeat thioredoxin-like 4 (TAIR:AT3G58620.1); Has 13751 Blast hits to 10343 proteins in 715 species: Archae - 525; Bacteria - 2944; Metazoa - 4001; Fungi - 1378; Plants - 1744; Viruses - 24; Other Eukaryotes - 3135 (source: NCBI BLink).
    NP_849557.1
    • Tetratricopeptide repeat (TPR)-like superfamily protein; FUNCTIONS IN: binding; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: tetratricopetide-repeat thioredoxin-like 4 (TAIR:AT3G58620.1); Has 7022 Blast hits to 5881 proteins in 426 species: Archae - 96; Bacteria - 637; Metazoa - 2797; Fungi - 861; Plants - 1268; Viruses - 25; Other Eukaryotes - 1338 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      14897346..14899121
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001036679.1 → NP_001031756.1  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031756.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4JQB2

    2. NM_179226.3 → NP_849557.1  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849557.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q94F21
      Conserved Domains (3) summary
      smart00028
      Location:148 → 179
      TPR; Tetratricopeptide repeats
      sd00006
      Location:105 → 133
      TPR; TPR repeat [structural motif]
      pfam13414
      Location:104 → 177
      TPR_11; TPR repeat

    3. NM_119194.5 → NP_194777.3  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194777.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V2X1, Q8LF50, Q9M0B2
      Conserved Domains (2) summary
      TIGR00990
      Location:25 → 244
      3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
      sd00006
      Location:105 → 133
      TPR; TPR repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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