U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    ern2 endoplasmic reticulum to nucleus signaling 2 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 779732, updated on 5-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ern2provided by Xenbase
    Official Full Name
    endoplasmic reticulum to nucleus signaling 2provided by Xenbase
    Primary source
    Xenbase:XB-GENE-4594134
    See related
    Ensembl:ENSXETG00000010337
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    ire1b; Ire1beta
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ern2 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 9 NC_030685.2 (21253733..21274093)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 9 NC_030685.1 (15400256..15420466)

    Chromosome 9 - NC_030685.2Genomic Context describing neighboring genes Neighboring gene NHL repeat containing 4 Neighboring gene phosphatidylinositol glycan anchor biosynthesis class Q Neighboring gene polo like kinase 1 Neighboring gene serine/threonine-protein kinase N2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC145511

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA nuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within endoplasmic reticulum unfolded protein response IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of nitrogen compound metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of primary metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to endoplasmic reticulum stress IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    serine/threonine-protein kinase/endoribonuclease IRE2
    Names
    endoplasmic reticulum (ER) to nucleus signalling 2
    NP_001072279.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001078811.1 → NP_001072279.1  serine/threonine-protein kinase/endoribonuclease IRE2 precursor

      See identical proteins and their annotated locations for NP_001072279.1

      Status: PROVISIONAL

      Source sequence(s)
      BC121289
      UniProtKB/TrEMBL
      A0A6I8RPG3, Q0VA24
      Related
      ENSXETP00000082502.2, ENSXETT00000104864.2
      Conserved Domains (3) summary
      cd09769
      Location:34 → 302
      Luminal_IRE1; The Luminal domain, a dimerization domain, of the Serine/Threonine protein kinase, Inositol-requiring protein 1
      cd10422
      Location:826 → 951
      RNase_Ire1; RNase domain (also known as the kinase extension nuclease domain) of Ire1
      cd13982
      Location:558 → 823
      STKc_IRE1; Catalytic domain of the Serine/Threonine kinase, Inositol-requiring protein 1

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030685.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      21253733..21274093
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.