SPINLW1 serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin) [Bos taurus (cattle)] - Gene

Summary

Gene symbol: SPINLW1
Gene description: serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)
See related: BGD:BT16406; Ensembl:ENSBTAG00000001495
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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Genomic context

Location:: chromosome: 13

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	13	NC_037340.1 (74396114..74413354, complement)

Chromosome 13 - NC_037340.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables serine-type endopeptidase inhibitor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of peptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: eppin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077062.2 → NP_001070530.1 eppin precursor

See identical proteins and their annotated locations for NP_001070530.1

Status: PROVISIONAL

Source sequence(s)

BC109986

UniProtKB/TrEMBL

Q32KP8

Related

ENSBTAP00000001959.3, ENSBTAT00000001959.4

Conserved Domains (1) summary

pfam00014
Location:76 → 127

Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037340.1 Reference ARS-UCD2.0 Primary Assembly

Range

74396114..74413354 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_025000848.2 → XP_024856616.1 eppin isoform X1

Conserved Domains (2) summary

pfam00014
Location:176 → 227

Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain

cl00156
Location:114 → 171

WAP; whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of ...