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    ano8b anoctamin 8b [ Danio rerio (zebrafish) ]

    Gene ID: 562782, updated on 27-Mar-2024

    Summary

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    Official Symbol
    ano8bprovided by ZNC
    Official Full Name
    anoctamin 8bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-121024-1
    See related
    Ensembl:ENSDARG00000077229 AllianceGenome:ZFIN:ZDB-GENE-121024-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ano8
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human ANO8 (anoctamin 8). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See ano8b in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (5965655..6001857, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (5968124..6004631, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene abhydrolase domain containing 8b Neighboring gene DET1 and DDB1 associated 1 Neighboring gene uncharacterized LOC110438878 Neighboring gene GTP binding protein 3, mitochondrial

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    anoctamin-8
    Names
    anoctamin 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      5965655..6001857 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021479701.1 → XP_021335376.1  anoctamin-8 isoform X1

      UniProtKB/TrEMBL
      A0A8N7UT44, E7F191
      Related
      ENSDARP00000099800.2, ENSDART00000108628.4
      Conserved Domains (1) summary
      pfam04547
      Location:258 → 870
      Anoctamin; Calcium-activated chloride channel

    2. XM_021479702.1 → XP_021335377.1  anoctamin-8 isoform X2

      UniProtKB/TrEMBL
      A0A8M6Z142
      Conserved Domains (1) summary
      pfam04547
      Location:258 → 799
      Anoctamin; Calcium-activated chloride channel

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394801.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      159892..196098 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_686156.9 → XP_691248.6  anoctamin-8 isoform X1

      UniProtKB/TrEMBL
      A0A8N7UT44, E7F191
      Conserved Domains (1) summary
      pfam04547
      Location:258 → 870
      Anoctamin; Calcium-activated chloride channel

    2. XM_017358269.2 → XP_017213758.1  anoctamin-8 isoform X2

      UniProtKB/TrEMBL
      A0A8M6Z142
      Conserved Domains (1) summary
      pfam04547
      Location:258 → 799
      Anoctamin; Calcium-activated chloride channel
    Nucleotide Protein
    Heading Accession and Version

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