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    hp1bp3 heterochromatin protein 1, binding protein 3 [ Danio rerio (zebrafish) ]

    Gene ID: 558102, updated on 11-Apr-2024

    Summary

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    Official Symbol
    hp1bp3provided by ZNC
    Official Full Name
    heterochromatin protein 1, binding protein 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060810-79
    See related
    Ensembl:ENSDARG00000044669 AllianceGenome:ZFIN:ZDB-GENE-060810-79
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb73a05; fb97a12; im:7157373; wu:fb73a05; wu:fb97a12
    Summary
    Predicted to enable DNA binding activity and nucleosome binding activity. Predicted to be involved in heterochromatin organization. Predicted to act upstream of or within nucleosome assembly and regulation of transcription, DNA-templated. Predicted to be part of nucleosome. Predicted to be active in chromosome and nucleus. Orthologous to human HP1BP3 (heterochromatin protein 1 binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 11
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (37612270..37629293)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (37345107..37362088)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene bassoon (presynaptic cytomatrix protein) b Neighboring gene si:dkey-61o18.2 Neighboring gene SH2 domain containing 5 Neighboring gene kinesin family member 17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RegenDbase: a comparative database of noncoding RNA regulation of tissue regeneration circuits across multiple taxa. King BL, et al. NPJ Regen Med, 2018. PMID 29872545, Free PMC Article
    2. Udu deficiency activates DNA damage checkpoint. Lim CH, et al. Mol Biol Cell, 2009 Oct. PMID 19656853, Free PMC Article
    3. Female Sex Development and Reproductive Duct Formation Depend on Wnt4a in Zebrafish. Kossack ME, et al. Genetics, 2019 Jan. PMID 30446521, Free PMC Article
    4. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article
    5. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in heterochromatin organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within nucleosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in chromosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    heterochromatin protein 1-binding protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001199725.1 → NP_001186654.1  heterochromatin protein 1-binding protein 3

      Status: VALIDATED

      Source sequence(s)
      CR847984
      UniProtKB/TrEMBL
      A0A8M1NV21
      Related
      ENSDARP00000071963.4, ENSDART00000077496.6
      Conserved Domains (1) summary
      pfam00538
      Location:136 → 210
      Linker_histone; linker histone H1 and H5 family

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      37612270..37629293
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005169409.4 → XP_005169466.2  heterochromatin protein 1-binding protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BGP7
      Related
      ENSDARP00000142470.2, ENSDART00000172899.2
      Conserved Domains (2) summary
      pfam00538
      Location:186 → 260
      Linker_histone; linker histone H1 and H5 family
      cl00478
      Location:57 → 137
      LGT; Prolipoprotein diacylglyceryl transferase
    Nucleotide Protein
    Heading Accession and Version

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