tubgcp4 tubulin gamma complex component 4 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tubgcp4provided by ZNC
Official Full Name: tubulin gamma complex component 4provided by ZNC
Primary source: ZFIN:ZDB-GENE-081022-124
See related: Ensembl:ENSDARG00000005374 AllianceGenome:ZFIN:ZDB-GENE-081022-124
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:194561; zgc:194580
Summary: Predicted to enable gamma-tubulin binding activity. Predicted to contribute to microtubule minus-end binding activity. Acts upstream of or within retinal cone cell differentiation and retinal rod cell differentiation. Predicted to be located in cytoplasm and microtubule cytoskeleton. Predicted to be part of gamma-tubulin complex. Predicted to be active in centrosome and equatorial microtubule organizing center. Human ortholog(s) of this gene implicated in microcephaly and chorioretinopathy 3. Orthologous to human TUBGCP4 (tubulin gamma complex associated protein 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (52933327..52949944, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (52662202..52678819, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc50a09 (e-PCR), detects polymorphism
- UniSTS:189261

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables gamma-tubulin binding	IBA Inferred from Biological aspect of Ancestor more info
enables gamma-tubulin binding	IEA Inferred from Electronic Annotation more info
contributes_to microtubule minus-end binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cytoplasmic microtubule organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in meiotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within microtubule cytoskeleton organization	IEA Inferred from Electronic Annotation more info
involved_in microtubule nucleation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within microtubule nucleation	IEA Inferred from Electronic Annotation more info
involved_in mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within retinal cone cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within retinal rod cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in spindle assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in centrosome	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
is_active_in equatorial microtubule organizing center	IBA Inferred from Biological aspect of Ancestor more info
part_of gamma-tubulin complex	IBA Inferred from Biological aspect of Ancestor more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
located_in microtubule organizing center	IEA Inferred from Electronic Annotation more info
located_in spindle pole	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: gamma-tubulin complex component 4

Names: tubulin, gamma complex associated protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.