snx8a sorting nexin 8a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: snx8aprovided by ZNC
Official Full Name: sorting nexin 8aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-031202-1
See related: Ensembl:ENSDARG00000074842 AllianceGenome:ZFIN:ZDB-GENE-031202-1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: snx8; cb1031
Summary: Predicted to enable phosphatidylinositol binding activity. Predicted to act upstream of or within protein transport and retrograde transport, endosome to Golgi. Predicted to be located in membrane. Is expressed in several structures, including EVL; periderm; tail bud; vasculature; and ventral mesoderm. Orthologous to human SNX8 (sorting nexin 8). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (42090418..42120172)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (41948560..41978314)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables phosphatidylinositol binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in early endosome to Golgi transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within retrograde transport, endosome to Golgi	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in early endosome membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: sorting nexin-8a

Names: sorting nexin 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001326490.1 → NP_001313419.1 sorting nexin-8a

Status: VALIDATED

Source sequence(s)

BX294380, BX510926

UniProtKB/TrEMBL

A0A8M1P923, F6NGW9

Related

ENSDARP00000103840.3, ENSDART00000109392.4

Conserved Domains (3) summary

cd06866
Location:132 → 241

PX_SNX8_Mvp1p_like; The phosphoinositide binding Phox Homology domain of Sorting Nexin 8 and yeast Mvp1p

cd07597
Location:258 → 502

BAR_SNX8; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 8

smart00027
Location:37 → 87

EH; Eps15 homology domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007114.7 Reference GRCz11 Primary Assembly

Range

42090418..42120172

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GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001162443.1: Suppressed sequence

Description

NM_001162443.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.