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    LAX1 lymphocyte transmembrane adaptor 1 [ Bos taurus (cattle) ]

    Gene ID: 540424, updated on 5-Mar-2024

    Summary

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    Official Symbol
    LAX1provided by VGNC
    Official Full Name
    lymphocyte transmembrane adaptor 1provided by VGNC
    Primary source
    VGNC:VGNC:30802
    See related
    BGD:BT13629; Ensembl:ENSBTAG00000012349
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    LAX
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 16
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 16 NC_037343.1 (1505874..1518392)

    Chromosome 16 - NC_037343.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene opticin Neighboring gene ATPase plasma membrane Ca2+ transporting 4 Neighboring gene uncharacterized LOC132342430 Neighboring gene uncharacterized LOC132342431 Neighboring gene zinc finger CCCH-type containing 11A Neighboring gene small nuclear ribonucleoprotein polypeptide E

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in antigen receptor-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lymphocyte activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of T cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lymphocyte transmembrane adapter 1
    Names
    membrane associated adaptor protein LAX
    membrane-associated adapter protein LAX

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001015674.1 → NP_001015674.1  lymphocyte transmembrane adapter 1

      See identical proteins and their annotated locations for NP_001015674.1

      Status: PROVISIONAL

      Source sequence(s)
      BT021859
      UniProtKB/Swiss-Prot
      Q58CT8
      Related
      ENSBTAP00000016385.4, ENSBTAT00000016385.5
      Conserved Domains (1) summary
      pfam15681
      Location:29 → 386
      LAX; Lymphocyte activation family X

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037343.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      1505874..1518392
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024976406.2 → XP_024832174.1  lymphocyte transmembrane adapter 1 isoform X2

      Related
      ENSBTAP00000083852.1, ENSBTAT00000135644.1
      Conserved Domains (1) summary
      pfam15681
      Location:29 → 348
      LAX; Lymphocyte activation family X

    2. XM_059875476.1 → XP_059731459.1  lymphocyte transmembrane adapter 1 isoform X1

      UniProtKB/Swiss-Prot
      Q58CT8

    3. XM_024976407.2 → XP_024832175.1  lymphocyte transmembrane adapter 1 isoform X3

      Conserved Domains (1) summary
      pfam15681
      Location:1 → 310
      LAX; Lymphocyte activation family X
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q58CT8.1 GenPept UniProtKB/Swiss-Prot:Q58CT8

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