U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    PTPRS protein tyrosine phosphatase receptor type S [ Bos taurus (cattle) ]

    Gene ID: 537480, updated on 3-Apr-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PTPRSprovided by VGNC
    Official Full Name
    protein tyrosine phosphatase receptor type Sprovided by VGNC
    Primary source
    VGNC:VGNC:33558
    See related
    BGD:BT27565; Ensembl:ENSBTAG00000018052
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 7
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (18936418..19047287)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112447541 Neighboring gene zinc and ring finger 4 Neighboring gene lysine demethylase 4B Neighboring gene ubiquitin like with PHD and ring finger domains 1 Neighboring gene arrestin domain containing 5

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    receptor-type tyrosine-protein phosphatase S
    XP_003586316.1
    XP_010805292.1
    XP_015327570.1
    XP_024850757.1
    XP_024850758.1
    XP_059744627.1
    XP_059744628.1
    XP_059744629.1
    XP_059744630.1
    XP_059744631.1
    XP_059744632.1
    XP_059744633.1
    XP_059744634.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      18936418..19047287
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059888644.1 → XP_059744627.1  receptor-type tyrosine-protein phosphatase S isoform X1

      Related
      ENSBTAP00000058723.2, ENSBTAT00000074579.2

    2. XM_015472084.3 → XP_015327570.1  receptor-type tyrosine-protein phosphatase S isoform X1

      UniProtKB/TrEMBL
      E1BIU8
      Related
      ENSBTAP00000042388.4, ENSBTAT00000044949.4
      Conserved Domains (8) summary
      cd05738
      Location:152 → 226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd05739
      Location:246 → 314
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:1379 → 1634
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:141 → 225
      IG_like; Immunoglobulin like
      cd00047
      Location:1405 → 1634
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:319 → 408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:32 → 120
      Ig; Immunoglobulin domain

    3. XM_059888646.1 → XP_059744629.1  receptor-type tyrosine-protein phosphatase S isoform X4

    4. XM_059888645.1 → XP_059744628.1  receptor-type tyrosine-protein phosphatase S isoform X2

    5. XM_059888647.1 → XP_059744630.1  receptor-type tyrosine-protein phosphatase S isoform X5

    6. XM_010806990.4 → XP_010805292.1  receptor-type tyrosine-protein phosphatase S isoform X3

      See identical proteins and their annotated locations for XP_010805292.1

      UniProtKB/TrEMBL
      E1BIU8
      Conserved Domains (5) summary
      cd05739
      Location:246 → 314
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:1370 → 1625
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00063
      Location:319 → 408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain
      cd05738
      Location:152 → 226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR

    7. XM_024994989.2 → XP_024850757.1  receptor-type tyrosine-protein phosphatase S isoform X6

      UniProtKB/TrEMBL
      E1BIU8
      Related
      ENSBTAP00000061608.2, ENSBTAT00000074444.2
      Conserved Domains (5) summary
      cd05739
      Location:246 → 314
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:1354 → 1609
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00063
      Location:319 → 408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain
      cd05738
      Location:152 → 226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR

    8. XM_059888648.1 → XP_059744631.1  receptor-type tyrosine-protein phosphatase S isoform X7

      Related
      ENSBTAP00000064107.2, ENSBTAT00000070996.2

    9. XM_059888649.1 → XP_059744632.1  receptor-type tyrosine-protein phosphatase S isoform X8

    10. XM_024994990.2 → XP_024850758.1  receptor-type tyrosine-protein phosphatase S isoform X9

      UniProtKB/TrEMBL
      A0A3Q1LNY4
      Related
      ENSBTAP00000099656.1, ENSBTAT00000098543.1
      Conserved Domains (5) summary
      cd05739
      Location:246 → 314
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:1310 → 1565
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00063
      Location:319 → 408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain
      cd05738
      Location:152 → 226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR

    11. XM_003586268.6 → XP_003586316.1  receptor-type tyrosine-protein phosphatase S isoform X11

      See identical proteins and their annotated locations for XP_003586316.1

      UniProtKB/TrEMBL
      A0A3Q1MJQ2
      Related
      ENSBTAP00000071603.2, ENSBTAT00000075329.2
      Conserved Domains (6) summary
      cd05739
      Location:246 → 314
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:1232 → 1491
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:971 → 1200
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:319 → 408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain
      cd05738
      Location:152 → 226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR

    12. XM_059888650.1 → XP_059744633.1  receptor-type tyrosine-protein phosphatase S isoform X10

    13. XM_059888651.1 → XP_059744634.1  receptor-type tyrosine-protein phosphatase S isoform X12

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.