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    PTPRR protein tyrosine phosphatase receptor type R [ Bos taurus (cattle) ]

    Gene ID: 536337, updated on 5-Mar-2024

    Summary

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    Official Symbol
    PTPRRprovided by VGNC
    Official Full Name
    protein tyrosine phosphatase receptor type Rprovided by VGNC
    Primary source
    VGNC:VGNC:33557
    See related
    BGD:BT25403; Ensembl:ENSBTAG00000015311
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    PCPTP1
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (42611524..42884727)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene copine 8 Neighboring gene uncharacterized LOC132345280 Neighboring gene 5S ribosomal RNA Neighboring gene uncharacterized LOC112446692 Neighboring gene protein tyrosine phosphatase receptor type B Neighboring gene uncharacterized LOC132345281 Neighboring gene microRNA mir-2284z-5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    receptor-type tyrosine-protein phosphatase R
    Names
    protein tyrosine phosphatase, receptor type, Q
    NP_001015662.1
    NP_001106732.1
    XP_010803381.1
    XP_010803382.1
    XP_024847710.1
    XP_059742550.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001015662.1 → NP_001015662.1  receptor-type tyrosine-protein phosphatase R isoform 1

      See identical proteins and their annotated locations for NP_001015662.1

      Status: PROVISIONAL

      Source sequence(s)
      BT020955
      UniProtKB/TrEMBL
      A0A3Q1MLA3, Q5E9G5
      Conserved Domains (2) summary
      smart00194
      Location:145 → 397
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:170 → 397
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

    2. NM_001113261.1 → NP_001106732.1  receptor-type tyrosine-protein phosphatase R isoform 2 precursor

      See identical proteins and their annotated locations for NP_001106732.1

      Status: PROVISIONAL

      Source sequence(s)
      BC142472
      UniProtKB/TrEMBL
      A5PKF8, F1MU02
      Related
      ENSBTAP00000020359.5, ENSBTAT00000020359.7
      Conserved Domains (2) summary
      smart00194
      Location:390 → 642
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:415 → 642
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      42611524..42884727
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059886567.1 → XP_059742550.1  receptor-type tyrosine-protein phosphatase R isoform X1

      Related
      ENSBTAP00000084089.1, ENSBTAT00000103522.1

    2. XM_010805079.3 → XP_010803381.1  receptor-type tyrosine-protein phosphatase R isoform X2

      Conserved Domains (2) summary
      smart00194
      Location:352 → 604
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:377 → 604
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

    3. XM_010805080.4 → XP_010803382.1  receptor-type tyrosine-protein phosphatase R isoform X3

      Related
      ENSBTAP00000091668.1, ENSBTAT00000101385.1
      Conserved Domains (2) summary
      smart00194
      Location:272 → 524
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:297 → 524
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

    4. XM_024991942.2 → XP_024847710.1  receptor-type tyrosine-protein phosphatase R isoform X4

      UniProtKB/TrEMBL
      A0A3Q1MLA3
      Related
      ENSBTAP00000099856.1, ENSBTAT00000099142.1
      Conserved Domains (1) summary
      cd00047
      Location:170 → 397
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    Nucleotide Protein Strain
    Heading Accession and Version

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