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    ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif 20 [ Bos taurus (cattle) ]

    Gene ID: 536137, updated on 5-Mar-2024

    Summary

    Official Symbol
    ADAMTS20provided by VGNC
    Official Full Name
    ADAM metallopeptidase with thrombospondin type 1 motif 20provided by VGNC
    Primary source
    VGNC:VGNC:25625
    See related
    BGD:BT19076; Ensembl:ENSBTAG00000000395
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    Location:
    chromosome: 5
    Exon count:
    40
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (36904946..37121155)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene interleukin 1 receptor associated kinase 4 Neighboring gene pseudouridine synthase 7 like Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene dnaJ homolog subfamily A member 3, mitochondrial-like Neighboring gene U6 spliceosomal RNA Neighboring gene N-acetyltransferase ESCO2

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    General protein information

    Preferred Names
    A disintegrin and metalloproteinase with thrombospondin motifs 20

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206093.2NP_001193022.1  A disintegrin and metalloproteinase with thrombospondin motifs 20 precursor

      See identical proteins and their annotated locations for NP_001193022.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000005
      UniProtKB/TrEMBL
      E1B900
      Related
      ENSBTAP00000036833.2, ENSBTAT00000036986.3
      Conserved Domains (6) summary
      smart00209
      Location:563615
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:262468
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam01421
      Location:262471
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:64185
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:725843
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam08685
      Location:17181914
      GON; GON domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      36904946..37121155
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024991940.1XP_024847708.1  A disintegrin and metalloproteinase with thrombospondin motifs 20 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LQP7
      Conserved Domains (6) summary
      smart00209
      Location:563615
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:262468
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      PTZ00441
      Location:11141233
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      pfam01562
      Location:41186
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:725843
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam08685
      Location:16421838
      GON; GON domain
    2. XM_024991941.2XP_024847709.1  A disintegrin and metalloproteinase with thrombospondin motifs 20 isoform X2

      Conserved Domains (5) summary
      smart00209
      Location:199251
      TSP1; Thrombospondin type 1 repeats
      PTZ00441
      Location:826945
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      pfam05986
      Location:361479
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam08685
      Location:13541550
      GON; GON domain
      cl00064
      Location:48104
      ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...