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    NECTIN1 nectin cell adhesion molecule 1 [ Bos taurus (cattle) ]

    Gene ID: 533492, updated on 5-Mar-2024

    Summary

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    Official Symbol
    NECTIN1provided by VGNC
    Official Full Name
    nectin cell adhesion molecule 1provided by VGNC
    Primary source
    VGNC:VGNC:54888
    See related
    BGD:BT21648; Ensembl:ENSBTAG00000015939
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    HVEC; prr1; PVRL1
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 15
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (30213687..30281883, complement)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101903835 Neighboring gene Thy-1 cell surface antigen Neighboring gene microRNA mir-378b Neighboring gene uncharacterized LOC132342281 Neighboring gene uncharacterized LOC112441621

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Porcine HveC, a member of the highly conserved HveC/nectin 1 family, is a functional alphaherpesvirus receptor. Milne RS, et al. Virology, 2001 Mar 15. PMID 11277703
    2. Host range of poliovirus is restricted to simians because of a rapid sequence change of the poliovirus receptor gene during evolution. Ida-Hosonuma M, et al. Arch Virol, 2003 Jan. PMID 12536294
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to cell junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nectin-1
    Names
    herpesvirus entry mediator C
    nectin
    poliovirus receptor related protein
    poliovirus receptor-related 1 (herpesvirus entry mediator C)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206022.3 → NP_001192951.1  nectin-1 precursor

      See identical proteins and their annotated locations for NP_001192951.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000015
      UniProtKB/TrEMBL
      A0A3Q1LI53, F1MQJ3
      Related
      ENSBTAP00000085266.1, ENSBTAT00000112262.1
      Conserved Domains (4) summary
      cd05886
      Location:45 → 143
      Ig1_Nectin-1_like; First immunoglobulin (Ig) domain of nectin-1 (also known as poliovirus receptor related protein 1, or as CD111) and similar proteins
      cd05890
      Location:146 → 243
      Ig2_Nectin-1_like; Second immunoglobulin (Ig) domain of nectin-1 (also known as poliovirus receptor related protein 1, or as CD111) and similar proteins
      smart00408
      Location:264 → 323
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:38 → 142
      IG_like; Immunoglobulin like

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      30213687..30281883 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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