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    ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13 [ Bos taurus (cattle) ]

    Gene ID: 532272, updated on 5-Mar-2024

    Summary

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    Official Symbol
    ADAMTS13provided by VGNC
    Official Full Name
    ADAM metallopeptidase with thrombospondin type 1 motif 13provided by VGNC
    Primary source
    VGNC:VGNC:25617
    See related
    BGD:BT12970; Ensembl:ENSBTAG00000015093
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 11
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (104318041..104351583)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene surfeit 2 Neighboring gene surfeit 4 Neighboring gene serine/threonine kinase like domain containing 1 Neighboring gene REX4 homolog, 3'-5' exonuclease Neighboring gene calcium channel flower domain containing 1 Neighboring gene solute carrier family 2 member 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A disintegrin and metalloproteinase with thrombospondin motifs 13
    XP_024855422.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      104318041..104351583
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024999654.2 → XP_024855422.1  A disintegrin and metalloproteinase with thrombospondin motifs 13

      Related
      ENSBTAP00000066754.2, ENSBTAT00000073324.2
      Conserved Domains (4) summary
      smart00209
      Location:392 → 444
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:82 → 288
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam05986
      Location:562 → 686
      ADAM_spacer1; ADAM-TS Spacer 1
      cl25800
      Location:747 → 892
      GGN; Gametogenetin
    Nucleotide Protein Strain
    Heading Accession and Version

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