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    WDR59 WD repeat domain 59 [ Bos taurus (cattle) ]

    Gene ID: 526642, updated on 3-Apr-2024

    Summary

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    Official Symbol
    WDR59provided by VGNC
    Official Full Name
    WD repeat domain 59provided by VGNC
    Primary source
    VGNC:VGNC:36907
    See related
    BGD:BT13780; Ensembl:ENSBTAG00000016878
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 18
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (2257648..2339536, complement)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene mixed lineage kinase domain like pseudokinase Neighboring gene fatty acid 2-hydroxylase Neighboring gene uncharacterized LOC132342771 Neighboring gene zinc and ring finger 1 Neighboring gene lactate dehydrogenase D

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GATOR2 complex protein WDR59; GATOR complex protein WDR59

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101130.1 → NP_001094600.1  GATOR2 complex protein WDR59

      See identical proteins and their annotated locations for NP_001094600.1

      Status: PROVISIONAL

      Source sequence(s)
      BC151595
      UniProtKB/TrEMBL
      A0A3Q1M2Y2, A7MBJ6
      Related
      ENSBTAP00000067577.2, ENSBTAT00000071782.2
      Conserved Domains (4) summary
      smart00591
      Location:394 → 494
      RWD; domain in RING finger and WD repeat containing proteins and DEXDc-like helicases subfamily related to the UBCc domain
      COG2319
      Location:34 → 354
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:62 → 103
      7WD40; WD40 repeat [structural motif]
      cd16692
      Location:922 → 968
      mRING-H2-C3H3C2_WDR59; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein 59 (WDR59) and similar proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      2257648..2339536 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059876780.1 → XP_059732763.1  GATOR complex protein WDR59 isoform X3

    2. XM_005218355.5 → XP_005218412.1  GATOR complex protein WDR59 isoform X1

      See identical proteins and their annotated locations for XP_005218412.1

      UniProtKB/TrEMBL
      A0A3Q1LY65, A0A3Q1M2Y2
      Related
      ENSBTAP00000060566.1, ENSBTAT00000074610.2
      Conserved Domains (4) summary
      smart00591
      Location:394 → 494
      RWD; domain in RING finger and WD repeat containing proteins and DEXDc-like helicases subfamily related to the UBCc domain
      COG2319
      Location:34 → 354
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:62 → 103
      7WD40; WD40 repeat [structural motif]
      cd16692
      Location:941 → 987
      mRING-H2-C3H3C2_WDR59; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein 59 (WDR59) and similar proteins

    3. XM_059876777.1 → XP_059732760.1  GATOR complex protein WDR59 isoform X2

      Related
      ENSBTAP00000022452.5, ENSBTAT00000022452.6

    4. XM_059876779.1 → XP_059732762.1  GATOR complex protein WDR59 isoform X2

      Related
      ENSBTAP00000090582.1, ENSBTAT00000089506.1

    5. XM_059876778.1 → XP_059732761.1  GATOR complex protein WDR59 isoform X2

    6. XM_059876781.1 → XP_059732764.1  GATOR complex protein WDR59 isoform X4

    7. XM_059876783.1 → XP_059732766.1  GATOR complex protein WDR59 isoform X5

    8. XM_059876782.1 → XP_059732765.1  GATOR complex protein WDR59 isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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