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    PXDN peroxidasin [ Bos taurus (cattle) ]

    Gene ID: 515860, updated on 5-Mar-2024

    Summary

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    Official Symbol
    PXDNprovided by VGNC
    Official Full Name
    peroxidasinprovided by VGNC
    Primary source
    VGNC:VGNC:106885
    See related
    BGD:BT13458; Ensembl:ENSBTAG00000050986
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 8
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (112102926..112167795)

    Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene myelin transcription factor 1 like Neighboring gene uncharacterized LOC112447855 Neighboring gene uncharacterized LOC112447856 Neighboring gene uncharacterized LOC132346027 Neighboring gene thyroid peroxidase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    peroxidasin homolog
    XP_010799143.1
    XP_010799144.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      112102926..112167795
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010800841.4 → XP_010799143.1  peroxidasin homolog isoform X1

      See identical proteins and their annotated locations for XP_010799143.1

      UniProtKB/TrEMBL
      A0A3Q1LMN6
      Related
      ENSBTAP00000057983.2, ENSBTAT00000073028.2
      Conserved Domains (12) summary
      cd05745
      Location:443 → 516
      Ig3_Peroxidasin; Third immunoglobulin (Ig)-like domain of peroxidasin
      cd05746
      Location:539 → 607
      Ig4_Peroxidasin; Fourth immunoglobulin (Ig)-like domain of peroxidasin
      cd09826
      Location:860 → 1300
      peroxidasin_like; Animal heme peroxidase domain of peroxidasin and related proteins
      pfam07679
      Location:430 → 516
      I-set; Immunoglobulin I-set domain
      sd00031
      Location:61 → 108
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:85 → 105
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00093
      Location:1415 → 1466
      VWC; von Willebrand factor type C domain
      pfam03098
      Location:738 → 1279
      An_peroxidase; Animal haem peroxidase
      pfam12799
      Location:132 → 172
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:108 → 167
      LRR_8; Leucine rich repeat
      cl11960
      Location:343 → 426
      Ig; Immunoglobulin domain
      cl15307
      Location:189 → 240
      TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

    2. XM_010800842.4 → XP_010799144.1  peroxidasin homolog isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MSA0
      Related
      ENSBTAP00000072857.2, ENSBTAT00000075716.2
      Conserved Domains (12) summary
      cd05745
      Location:419 → 492
      Ig3_Peroxidasin; Third immunoglobulin (Ig)-like domain of peroxidasin
      cd05746
      Location:515 → 583
      Ig4_Peroxidasin; Fourth immunoglobulin (Ig)-like domain of peroxidasin
      cd09826
      Location:836 → 1276
      peroxidasin_like; Animal heme peroxidase domain of peroxidasin and related proteins
      pfam07679
      Location:406 → 492
      I-set; Immunoglobulin I-set domain
      sd00031
      Location:61 → 75
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:42 → 60
      LRR_RI; leucine-rich repeat [structural motif]
      pfam00093
      Location:1391 → 1442
      VWC; von Willebrand factor type C domain
      pfam03098
      Location:714 → 1255
      An_peroxidase; Animal haem peroxidase
      pfam12799
      Location:107 → 148
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:108 → 167
      LRR_8; Leucine rich repeat
      cl11960
      Location:319 → 402
      Ig; Immunoglobulin domain
      cl15307
      Location:165 → 216
      TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    Nucleotide Protein Strain
    Heading Accession and Version

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