U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    ASB14 ankyrin repeat and SOCS box containing 14 [ Bos taurus (cattle) ]

    Gene ID: 509431, updated on 3-Apr-2024

    Summary

    Official Symbol
    ASB14provided by VGNC
    Official Full Name
    ankyrin repeat and SOCS box containing 14provided by VGNC
    Primary source
    VGNC:VGNC:26191
    See related
    BGD:BT22577; Ensembl:ENSBTAG00000016013
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    DNAH12
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    chromosome: 22
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (43831544..43862751)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene dynein axonemal heavy chain 12 Neighboring gene small ribosomal subunit protein eS27-like Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene HESX homeobox 1

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    dynein axonemal heavy chain 12; ankyrin repeat and SOCS box protein 14
    Names
    ASB-14
    ankyrin repeat and SOCS box-containing protein 14
    axonemal beta dynein heavy chain 12
    ciliary dynein heavy chain 12
    dynein heavy chain 12, axonemal

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035070.2NP_001030242.2  dynein axonemal heavy chain 12

      See identical proteins and their annotated locations for NP_001030242.2

      Status: VALIDATED

      Source sequence(s)
      BC148874
      UniProtKB/TrEMBL
      A0A3Q1N243, G8JKY1
      Related
      ENSBTAP00000021315.6, ENSBTAT00000021315.6
      Conserved Domains (4) summary
      cd00204
      Location:113233
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd03730
      Location:526582
      SOCS_ASB14; SOCS (suppressors of cytokine signaling) box of ASB14-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...
      sd00045
      Location:181210
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:57144
      Ank_2; Ankyrin repeats (3 copies)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      43831544..43862751
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059879576.1XP_059735559.1  ankyrin repeat and SOCS box protein 14 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1N243
    2. XM_059879577.1XP_059735560.1  ankyrin repeat and SOCS box protein 14 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1N243
    3. XM_059879579.1XP_059735562.1  ankyrin repeat and SOCS box protein 14 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1N243
    4. XM_059879578.1XP_059735561.1  ankyrin repeat and SOCS box protein 14 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1N243
    5. XM_059879580.1XP_059735563.1  ankyrin repeat and SOCS box protein 14 isoform X2

    6. XM_059879581.1XP_059735564.1  ankyrin repeat and SOCS box protein 14 isoform X3