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    VARS1 valyl-tRNA synthetase 1 [ Bos taurus (cattle) ]

    Gene ID: 505556, updated on 5-Mar-2024

    Summary

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    Official Symbol
    VARS1provided by VGNC
    Official Full Name
    valyl-tRNA synthetase 1provided by VGNC
    Primary source
    VGNC:VGNC:36765
    See related
    BGD:BT11215; Ensembl:ENSBTAG00000005631
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    VARS
    Orthologs
    human mouse all
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    Genomic context

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    See VARS1 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (27533360..27546153)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene heat shock protein family A (Hsp70) member 1A Neighboring gene heat shock 70kDa protein 1-like Neighboring gene LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated Neighboring gene von Willebrand factor A domain containing 7 Neighboring gene suppressor APC domain containing 1 Neighboring gene mutS homolog 5 Neighboring gene chloride intracellular channel 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables aminoacyl-tRNA editing activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables valine-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in valyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    valine--tRNA ligase
    XP_024839848.1
    XP_024839849.1
    XP_024839850.1
    XP_024839851.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      27533360..27546153
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024984080.2 → XP_024839848.1  valine--tRNA ligase isoform X1

      Conserved Domains (3) summary
      cl02776
      Location:195 → 268
      GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family
      cl26128
      Location:338 → 1320
      tRNA-synt_1g; tRNA synthetases class I (M)
      cl26386
      Location:56 → 223
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

    2. XM_024984081.2 → XP_024839849.1  valine--tRNA ligase isoform X2

      Conserved Domains (3) summary
      cl02776
      Location:195 → 268
      GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family
      cl26128
      Location:337 → 1319
      tRNA-synt_1g; tRNA synthetases class I (M)
      cl26386
      Location:56 → 223
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

    3. XM_024984082.2 → XP_024839850.1  valine--tRNA ligase isoform X3

      Conserved Domains (2) summary
      cl02776
      Location:92 → 213
      GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family
      cl26128
      Location:283 → 1265
      tRNA-synt_1g; tRNA synthetases class I (M)

    4. XM_024984083.2 → XP_024839851.1  valine--tRNA ligase isoform X4

      UniProtKB/TrEMBL
      E1BLV6
      Related
      ENSBTAP00000007404.7, ENSBTAT00000007404.7
      Conserved Domains (2) summary
      cl02776
      Location:92 → 213
      GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family
      cl26128
      Location:282 → 1264
      tRNA-synt_1g; tRNA synthetases class I (M)
    Nucleotide Protein Strain
    Heading Accession and Version

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