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    casc3 CASC3, exon junction complex subunit [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 503560, updated on 5-Mar-2024

    Summary

    Official Symbol
    casc3provided by Xenbase
    Official Full Name
    CASC3, exon junction complex subunitprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-969211
    See related
    Ensembl:ENSXETG00000024395
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    btz; mln51; StMLN51; barentsz
    Orthologs
    NEW
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    Genomic context

    Location:
    chromosome: 10
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 10 NC_030686.2 (8968567..8997831, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016683386.1 (410009..441437)

    Chromosome 10 - NC_030686.2Genomic Context describing neighboring genes Neighboring gene WAS/WASL interacting protein family member 2 Neighboring gene Rap guanine nucleotide exchange factor like 1 Neighboring gene male-specific lethal 1 homolog Neighboring gene nuclear receptor subfamily 1 group D member 1

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within mRNA transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of U2-type catalytic step 1 spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic ribonucleoprotein granule IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic stress granule IEA
    Inferred from Electronic Annotation
    more info
     
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
     
    part_of exon-exon junction complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of exon-exon junction complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein CASC3
    Names
    Cancer susceptibility candidate gene 3 protein homolog
    Metastatic lymph node protein 51 homolog
    Protein MLN 51 homolog
    cancer susceptibility 3
    cancer susceptibility candidate 3
    metastatic lymph node 51

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012652.1NP_001012670.1  protein CASC3

      See identical proteins and their annotated locations for NP_001012670.1

      Status: PROVISIONAL

      Source sequence(s)
      BN000153
      UniProtKB/Swiss-Prot
      Q5CZI8
      UniProtKB/TrEMBL
      A0A803KJS2
      Related
      ENSXETP00000052759.4, ENSXETT00000052759.5
      Conserved Domains (1) summary
      smart01044
      Location:125228
      Btz; CASC3/Barentsz eIF4AIII binding

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030686.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      8968567..8997831 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012971726.3XP_012827180.2  protein CASC3 isoform X1

      UniProtKB/TrEMBL
      A0A6I8S9U9, A0A6I8SJN0
      Related
      ENSXETP00000091593.2, ENSXETT00000094787.2
      Conserved Domains (1) summary
      smart01044
      Location:125228
      Btz; CASC3/Barentsz eIF4AIII binding
    2. XM_012971728.3XP_012827182.2  protein CASC3 isoform X2

      UniProtKB/TrEMBL
      A0A6I8S658, A0A6I8SJN0
      Related
      ENSXETP00000088694.2, ENSXETT00000091686.2
      Conserved Domains (1) summary
      smart01044
      Location:125228
      Btz; CASC3/Barentsz eIF4AIII binding

    RNA

    1. XR_001923301.2 RNA Sequence