dstyk dual serine/threonine and tyrosine protein kinase [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: dstykprovided by Xenbase
Official Full Name: dual serine/threonine and tyrosine protein kinaseprovided by Xenbase
Primary source: Xenbase:XB-GENE-971397
See related: Ensembl:ENSXETG00000000902
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: ripk5
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	2	NC_030678.2 (72537550..72577374)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	2	NC_030678.1 (64174810..64213331)

Chromosome 2 - NC_030678.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine/tyrosine kinase activity	IEA Inferred from Electronic Annotation more info
enables protein tyrosine kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cellular response to fibroblast growth factor stimulus	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within embryonic organ development	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of apoptotic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of ERK1 and ERK2 cascade	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of fibroblast growth factor receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in anchoring junction	IEA Inferred from Electronic Annotation more info
located_in apical plasma membrane	IEA Inferred from Electronic Annotation more info
located_in apical plasma membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in basolateral plasma membrane	IEA Inferred from Electronic Annotation more info
located_in basolateral plasma membrane	ISS Inferred from Sequence or Structural Similarity more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: dual serine/threonine and tyrosine protein kinase

Names: dusty PK; dusty protein kinase; receptor-interacting serine/threonine-protein kinase 5

NP_001007477.1

EC 2.7.12.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001007476.1 → NP_001007477.1 dual serine/threonine and tyrosine protein kinase

See identical proteins and their annotated locations for NP_001007477.1

Status: PROVISIONAL

Source sequence(s)

AY429679

UniProtKB/Swiss-Prot

Q67E00

UniProtKB/TrEMBL

A8WGE5

Related

ENSXETP00000061939.1, ENSXETT00000063117.3

Conserved Domains (2) summary

smart00220
Location:644 → 888

S_TKc; Serine/Threonine protein kinases, catalytic domain

cd13975
Location:642 → 903

PKc_Dusty; Catalytic domain of the Dual-specificity Protein Kinase, Dusty