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    LRCH2 leucine rich repeats and calponin homology domain containing 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 492078, updated on 5-Mar-2024

    Summary

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    Official Symbol
    LRCH2provided by VGNC
    Official Full Name
    leucine rich repeats and calponin homology domain containing 2provided by VGNC
    Primary source
    VGNC:VGNC:42758
    See related
    Ensembl:ENSCAFG00845016493
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: X
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (89582527..89705174, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (73987375..74111357, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (88532967..88658326, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (87025537..87149668, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (88699900..88823764, complement)

    Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene 5-hydroxytryptamine receptor 2C Neighboring gene microRNA mir-448 Neighboring gene U6 spliceosomal RNA Neighboring gene interleukin 13 receptor subunit alpha 2 Neighboring gene transcription factor BTF3-like Neighboring gene small nucleolar RNA SNORA35 Neighboring gene RNA-binding protein EWS-like Neighboring gene leucine zipper protein 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leucine-rich repeat and calponin homology domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051843.1 Reference ROS_Cfam_1.0

      Range
      89582527..89705174 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038449206.1 → XP_038305134.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3P2I3
      Related
      ENSCAFP00845023074.1, ENSCAFT00845029352.1
      Conserved Domains (3) summary
      PRK15370
      Location:93 → 288
      PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
      sd00033
      Location:117 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      cd21271
      Location:611 → 721
      CH_LRCH2; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 2

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049299.1 Alternate UMICH_Zoey_3.1

      Range
      87025537..87149668 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038524136.1 → XP_038380064.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X2

      Conserved Domains (3) summary
      PRK15370
      Location:93 → 288
      PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
      sd00033
      Location:117 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      cd21271
      Location:694 → 804
      CH_LRCH2; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 2

    2. XM_038524134.1 → XP_038380062.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X2

      Conserved Domains (3) summary
      PRK15370
      Location:93 → 288
      PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
      sd00033
      Location:117 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      cd21271
      Location:694 → 804
      CH_LRCH2; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 2

    3. XM_038524140.1 → XP_038380068.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X6

    4. XM_038524137.1 → XP_038380065.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X3

    5. XM_038524141.1 → XP_038380069.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X7

    6. XM_038524138.1 → XP_038380066.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X4

    7. XM_038524139.1 → XP_038380067.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X5

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

      Range
      88699900..88823764 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038652625.1 → XP_038508553.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X8

      Conserved Domains (3) summary
      PRK15370
      Location:93 → 288
      PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
      sd00033
      Location:117 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      cd21271
      Location:694 → 804
      CH_LRCH2; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 2

    2. XM_038652624.1 → XP_038508552.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X8

      Conserved Domains (3) summary
      PRK15370
      Location:93 → 288
      PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
      sd00033
      Location:117 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      cd21271
      Location:694 → 804
      CH_LRCH2; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 2

    3. XM_038652629.1 → XP_038508557.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X12

    4. XM_038652626.1 → XP_038508554.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X9

    5. XM_038652630.1 → XP_038508558.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X13

    6. XM_038652627.1 → XP_038508555.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X10

    7. XM_038652628.1 → XP_038508556.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X11

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

      Range
      88532967..88658326 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038588110.1 → XP_038444038.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X14

      UniProtKB/TrEMBL
      A0A8C0SUM8, A0A8P0SMM2
      Conserved Domains (3) summary
      PRK15370
      Location:93 → 288
      PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
      sd00033
      Location:117 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      cd21271
      Location:694 → 804
      CH_LRCH2; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 2

    2. XM_038588109.1 → XP_038444037.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X14

      UniProtKB/TrEMBL
      A0A8C0SUM8, A0A8P0SMM2
      Conserved Domains (3) summary
      PRK15370
      Location:93 → 288
      PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
      sd00033
      Location:117 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      cd21271
      Location:694 → 804
      CH_LRCH2; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 2

    3. XM_038588114.1 → XP_038444042.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X18

      UniProtKB/TrEMBL
      A0A8C0SUM8, A0A8P0SMM2

    4. XM_038588111.1 → XP_038444039.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X15

      UniProtKB/TrEMBL
      A0A8C0SUV9, A0A8P0NSW6

    5. XM_038588115.1 → XP_038444043.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X19

      UniProtKB/TrEMBL
      A0A8C0SUM8, A0A8P0SMM2

    6. XM_038588112.1 → XP_038444040.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X16

      UniProtKB/TrEMBL
      A0A8C0SUM8, A0A8P0SMM2

    7. XM_038588113.1 → XP_038444041.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X17

      UniProtKB/TrEMBL
      A0A8C0SUV9, A0A8P0NSW6

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      73987375..74111357 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022415711.2 → XP_022271419.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X20

      UniProtKB/TrEMBL
      A0A8C0SUM8, A0A8P0SMM2
      Conserved Domains (3) summary
      PRK15370
      Location:93 → 288
      PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
      sd00033
      Location:117 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      cd21271
      Location:694 → 804
      CH_LRCH2; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 2

    2. XM_022415710.2 → XP_022271418.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X20

      UniProtKB/TrEMBL
      A0A8C0SUM8, A0A8P0SMM2
      Conserved Domains (3) summary
      PRK15370
      Location:93 → 288
      PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
      sd00033
      Location:117 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      cd21271
      Location:694 → 804
      CH_LRCH2; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 2

    3. XM_022415715.2 → XP_022271423.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X24

      UniProtKB/TrEMBL
      A0A8C0SUM8, A0A8P0SMM2
      Conserved Domains (3) summary
      smart00033
      Location:653 → 742
      CH; Calponin homology domain
      sd00033
      Location:117 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      cl26018
      Location:93 → 288
      NEL; C-terminal novel E3 ligase, LRR-interacting

    4. XM_022415712.2 → XP_022271420.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X21

      UniProtKB/TrEMBL
      A0A8C0SUV9, A0A8P0NSW6
      Conserved Domains (3) summary
      smart00033
      Location:684 → 773
      CH; Calponin homology domain
      sd00033
      Location:117 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      cl26018
      Location:93 → 288
      NEL; C-terminal novel E3 ligase, LRR-interacting

    5. XM_022415716.2 → XP_022271424.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X25

      UniProtKB/TrEMBL
      A0A8C0SUM8, A0A8P0SMM2
      Conserved Domains (3) summary
      smart00033
      Location:639 → 728
      CH; Calponin homology domain
      sd00033
      Location:117 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      cl26018
      Location:93 → 288
      NEL; C-terminal novel E3 ligase, LRR-interacting

    6. XM_022415713.2 → XP_022271421.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X22

      UniProtKB/TrEMBL
      A0A8C0SUM8, A0A8P0SMM2
      Conserved Domains (3) summary
      smart00033
      Location:675 → 764
      CH; Calponin homology domain
      sd00033
      Location:117 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      cl26018
      Location:93 → 288
      NEL; C-terminal novel E3 ligase, LRR-interacting

    7. XM_022415714.2 → XP_022271422.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X23

      UniProtKB/TrEMBL
      A0A8C0SUV9, A0A8P0NSW6
      Conserved Domains (3) summary
      smart00033
      Location:658 → 747
      CH; Calponin homology domain
      sd00033
      Location:117 → 137
      LRR_RI; leucine-rich repeat [structural motif]
      cl26018
      Location:93 → 288
      NEL; C-terminal novel E3 ligase, LRR-interacting
    Nucleotide Protein
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