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    RHPN1 rhophilin Rho GTPase binding protein 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 482076, updated on 5-Mar-2024

    Summary

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    Official Symbol
    RHPN1provided by VGNC
    Official Full Name
    rhophilin Rho GTPase binding protein 1provided by VGNC
    Primary source
    VGNC:VGNC:45567
    See related
    Ensembl:ENSCAFG00845015006
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 13
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 13 NC_051817.1 (37552809..37562692)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 13 NC_006595.4 (37033326..37043196)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 13 NC_049234.1 (37820507..37830374)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 13 NC_049273.1 (37224836..37234698)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 13 NC_049754.1 (37343369..37353204)

    Chromosome 13 - NC_051817.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111098582 Neighboring gene GLI family zinc finger 4 Neighboring gene uncharacterized LOC102152553 Neighboring gene MAF bZIP transcription factor A Neighboring gene zinc finger CCCH-type containing 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of stress fiber assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rhophilin-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051817.1 Reference ROS_Cfam_1.0

      Range
      37552809..37562692
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038685243.1 → XP_038541171.1  rhophilin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0SAF2
      Conserved Domains (3) summary
      cd09248
      Location:60 → 443
      BRO1_Rhophilin_1; Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin-1
      smart00228
      Location:464 → 538
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cl00087
      Location:1 → 56
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases

    2. XM_038685242.1 → XP_038541170.1  rhophilin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L4P2, A0A8I3NLJ1, A0A8I3NWK8, A0A8P0S788
      Related
      ENSCAFP00845021174.1, ENSCAFT00845026896.1
      Conserved Domains (3) summary
      cd09248
      Location:116 → 499
      BRO1_Rhophilin_1; Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin-1
      smart00228
      Location:520 → 594
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cl00087
      Location:28 → 112
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049273.1 Alternate UMICH_Zoey_3.1

      Range
      37224836..37234698
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038493409.1 → XP_038349337.1  rhophilin-1 isoform X2

      Conserved Domains (3) summary
      cd09248
      Location:60 → 443
      BRO1_Rhophilin_1; Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin-1
      smart00228
      Location:464 → 538
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cl00087
      Location:1 → 56
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases

    2. XM_038493408.1 → XP_038349336.1  rhophilin-1 isoform X1

      Conserved Domains (3) summary
      cd09248
      Location:116 → 499
      BRO1_Rhophilin_1; Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin-1
      smart00228
      Location:520 → 594
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cl00087
      Location:28 → 112
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049754.1 Alternate UNSW_CanFamBas_1.0

      Range
      37343369..37353204
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038619635.1 → XP_038475563.1  rhophilin-1 isoform X2

      Conserved Domains (3) summary
      cd09248
      Location:60 → 443
      BRO1_Rhophilin_1; Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin-1
      smart00228
      Location:464 → 538
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cl00087
      Location:1 → 56
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases

    2. XM_038619634.1 → XP_038475562.1  rhophilin-1 isoform X1

      Conserved Domains (3) summary
      cd09248
      Location:116 → 499
      BRO1_Rhophilin_1; Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin-1
      smart00228
      Location:520 → 594
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cl00087
      Location:28 → 112
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049234.1 Alternate UU_Cfam_GSD_1.0

      Range
      37820507..37830374
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038555732.1 → XP_038411660.1  rhophilin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0SAF2

    2. XM_038555731.1 → XP_038411659.1  rhophilin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8I3NWK8

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006595.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      37033326..37043196
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038430407.1 → XP_038286335.1  rhophilin-1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0SAF2
      Conserved Domains (3) summary
      cd09248
      Location:60 → 443
      BRO1_Rhophilin_1; Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin-1
      smart00228
      Location:464 → 538
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cl00087
      Location:1 → 56
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases

    2. XM_005628025.4 → XP_005628082.1  rhophilin-1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0L4P2, A0A8I3NLJ1, A0A8I3NWK8, A0A8P0S788
      Conserved Domains (3) summary
      cd09248
      Location:116 → 499
      BRO1_Rhophilin_1; Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin-1
      smart00228
      Location:520 → 594
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cl00087
      Location:28 → 112
      HR1; Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases
    Nucleotide Protein
    Heading Accession and Version

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