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    DAAM2 dishevelled associated activator of morphogenesis 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 481783, updated on 5-Mar-2024

    Summary

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    Official Symbol
    DAAM2provided by VGNC
    Official Full Name
    dishevelled associated activator of morphogenesis 2provided by VGNC
    Primary source
    VGNC:VGNC:39757
    See related
    Ensembl:ENSCAFG00845014494
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 12
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (9164538..9280343)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (8717558..8834912)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (8876888..8991550)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (8699229..8814909)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (8770162..8885461)

    Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111098249 Neighboring gene uncharacterized LOC102157226 Neighboring gene kinesin family member 6 Neighboring gene molybdenum cofactor synthesis 1 Neighboring gene uncharacterized LOC119874266 Neighboring gene uncharacterized LOC111098250

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of oligodendrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of non-canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    disheveled-associated activator of morphogenesis 2; LOW QUALITY PROTEIN: disheveled-associated activator of morphogenesis 2

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051816.1 Reference ROS_Cfam_1.0

      Range
      9164538..9280343
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038683434.1 → XP_038539362.1  disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RET8, A0A8C0TJF8, A0A8I3P2K9
      Related
      ENSCAFP00845020502.1, ENSCAFT00845026004.1
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    2. XM_038683435.1 → XP_038539363.1  disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RET8, A0A8C0TJF8, A0A8I3P2K9
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    3. XM_038683436.1 → XP_038539364.1  disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RET8, A0A8C0TJF8, A0A8I3P2K9
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    4. XM_038683438.1 → XP_038539366.1  disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RET8, A0A8C0TJF8, A0A8I3P2K9
      Related
      ENSCAFP00845020476.1, ENSCAFT00845025977.1
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    5. XM_038683437.1 → XP_038539365.1  disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RET8, A0A8C0TJF8, A0A8I3P2K9
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    6. XM_038683439.1 → XP_038539367.1  disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RET8, A0A8C0TJF8, A0A8I3P2K9
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    7. XM_038683440.1 → XP_038539368.1  disheveled-associated activator of morphogenesis 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0K4T0, A0A8C0TKF1, A0A8I3NJV8, A0A8P0N4Q4
      Related
      ENSCAFP00845020464.1, ENSCAFT00845025960.1
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 969
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049272.1 Alternate UMICH_Zoey_3.1

      Range
      8699229..8814909
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038491749.1 → XP_038347677.1  disheveled-associated activator of morphogenesis 2 isoform X1

      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    2. XM_038491750.1 → XP_038347678.1  disheveled-associated activator of morphogenesis 2 isoform X1

      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    3. XM_038491751.1 → XP_038347679.1  disheveled-associated activator of morphogenesis 2 isoform X1

      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    4. XM_038491753.1 → XP_038347681.1  disheveled-associated activator of morphogenesis 2 isoform X1

      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    5. XM_038491752.1 → XP_038347680.1  disheveled-associated activator of morphogenesis 2 isoform X1

      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    6. XM_038491754.1 → XP_038347682.1  disheveled-associated activator of morphogenesis 2 isoform X1

      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    7. XM_038491755.1 → XP_038347683.1  disheveled-associated activator of morphogenesis 2 isoform X2

      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 969
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

      Range
      8770162..8885461
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038617841.1 → XP_038473769.1  disheveled-associated activator of morphogenesis 2 isoform X1

    2. XM_038617842.1 → XP_038473770.1  disheveled-associated activator of morphogenesis 2 isoform X1

    3. XM_038617843.1 → XP_038473771.1  disheveled-associated activator of morphogenesis 2 isoform X1

    4. XM_038617845.1 → XP_038473773.1  disheveled-associated activator of morphogenesis 2 isoform X1

    5. XM_038617844.1 → XP_038473772.1  disheveled-associated activator of morphogenesis 2 isoform X1

    6. XM_038617846.1 → XP_038473774.1  disheveled-associated activator of morphogenesis 2 isoform X1

    7. XM_038617847.1 → XP_038473775.1  disheveled-associated activator of morphogenesis 2 isoform X2

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

      Range
      8876888..8991550
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038553978.1 → XP_038409906.1  LOW QUALITY PROTEIN: disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RET8, A0A8C0TJF8, A0A8I3P2K9
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      8717558..8834912
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038671148.1 → XP_038527076.1  disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RET8, A0A8C0TJF8, A0A8I3P2K9
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    2. XM_038671157.1 → XP_038527085.1  disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RET8, A0A8C0TJF8, A0A8I3P2K9
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    3. XM_005627294.4 → XP_005627351.1  disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RET8, A0A8C0TJF8, A0A8I3P2K9
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    4. XM_014118416.3 → XP_013973891.1  disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RET8, A0A8C0TJF8, A0A8I3P2K9
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    5. XM_038671164.1 → XP_038527092.1  disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RET8, A0A8C0TJF8, A0A8I3P2K9
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    6. XM_014118417.3 → XP_013973892.1  disheveled-associated activator of morphogenesis 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0RET8, A0A8C0TJF8, A0A8I3P2K9
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 978
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain

    7. XM_022426019.1 → XP_022281727.1  disheveled-associated activator of morphogenesis 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0K4T0, A0A8C0TKF1, A0A8I3NJV8, A0A8P0N4Q4
      Conserved Domains (3) summary
      pfam06367
      Location:231 → 435
      Drf_FH3; Diaphanous FH3 Domain
      pfam02181
      Location:595 → 969
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:43 → 228
      Drf_GBD; Diaphanous GTPase-binding Domain
    Nucleotide Protein
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