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    REXO5 RNA exonuclease 5 [ Canis lupus familiaris (dog) ]

    Gene ID: 479820, updated on 5-Mar-2024

    Summary

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    Official Symbol
    REXO5provided by VGNC
    Official Full Name
    RNA exonuclease 5provided by VGNC
    Primary source
    VGNC:VGNC:54063
    See related
    Ensembl:ENSCAFG00845007224
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 6
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (24661619..24705902, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (25945547..25989816, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (24741897..24786137, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (24462575..24506834, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (24357768..24402061, complement)

    Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene dynein axonemal heavy chain 3 Neighboring gene LYR motif containing 1 Neighboring gene defective in cullin neddylation 1 domain containing 3 Neighboring gene ERI1 exoribonuclease family member 2 Neighboring gene acyl-CoA synthetase medium chain family member 3 Neighboring gene uncharacterized LOC119872187 Neighboring gene THUMP domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative RNA exonuclease NEF-sp; RNA exonuclease 5
    Names
    exonuclease NEF-sp

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051810.1 Reference ROS_Cfam_1.0

      Range
      24661619..24705902 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038668966.1 → XP_038524894.1  RNA exonuclease 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PLF7, A0A8C0PNL5, A0A8I3N036, A0A8I3RTV6
      Conserved Domains (2) summary
      cd06145
      Location:230 → 378
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      cl17169
      Location:507 → 577
      RRM_SF; RNA recognition motif (RRM) superfamily

    2. XM_038668964.1 → XP_038524892.1  RNA exonuclease 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PLF7, A0A8C0PNL5, A0A8I3N036, A0A8I3RTV6
      Related
      ENSCAFP00845010101.1, ENSCAFT00845012959.1
      Conserved Domains (2) summary
      cd06145
      Location:230 → 378
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      cl17169
      Location:507 → 577
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_038668965.1 → XP_038524893.1  RNA exonuclease 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PLF7, A0A8C0PNL5, A0A8I3N036, A0A8I3RTV6
      Conserved Domains (2) summary
      cd06145
      Location:230 → 378
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      cl17169
      Location:507 → 577
      RRM_SF; RNA recognition motif (RRM) superfamily

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049266.1 Alternate UMICH_Zoey_3.1

      Range
      24462575..24506834 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038478921.1 → XP_038334849.1  RNA exonuclease 5 isoform X1

      Conserved Domains (2) summary
      cd06145
      Location:230 → 378
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      cl17169
      Location:507 → 577
      RRM_SF; RNA recognition motif (RRM) superfamily

    2. XM_038478918.1 → XP_038334846.1  RNA exonuclease 5 isoform X1

      Conserved Domains (2) summary
      cd06145
      Location:230 → 378
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      cl17169
      Location:507 → 577
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_038478919.1 → XP_038334847.1  RNA exonuclease 5 isoform X1

      Conserved Domains (2) summary
      cd06145
      Location:230 → 378
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      cl17169
      Location:507 → 577
      RRM_SF; RNA recognition motif (RRM) superfamily

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

      Range
      24357768..24402061 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038604248.1 → XP_038460176.1  RNA exonuclease 5 isoform X2

    2. XM_038604250.1 → XP_038460178.1  RNA exonuclease 5 isoform X1

      Conserved Domains (2) summary
      cd06145
      Location:230 → 378
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      cl17169
      Location:507 → 577
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_038604251.1 → XP_038460179.1  RNA exonuclease 5 isoform X1

      Conserved Domains (2) summary
      cd06145
      Location:230 → 378
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      cl17169
      Location:507 → 577
      RRM_SF; RNA recognition motif (RRM) superfamily

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

      Range
      24741897..24786137 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038540162.1 → XP_038396090.1  RNA exonuclease 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PLF7, A0A8C0PNL5, A0A8I3N036, A0A8I3RTV6
      Conserved Domains (2) summary
      cd06145
      Location:230 → 378
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      cl17169
      Location:507 → 577
      RRM_SF; RNA recognition motif (RRM) superfamily

    2. XM_038540160.1 → XP_038396088.1  RNA exonuclease 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PLF7, A0A8C0PNL5, A0A8I3N036, A0A8I3RTV6
      Conserved Domains (2) summary
      cd06145
      Location:230 → 378
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      cl17169
      Location:507 → 577
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_038540161.1 → XP_038396089.1  RNA exonuclease 5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PLF7, A0A8C0PNL5, A0A8I3N036, A0A8I3RTV6
      Conserved Domains (2) summary
      cd06145
      Location:230 → 378
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      cl17169
      Location:507 → 577
      RRM_SF; RNA recognition motif (RRM) superfamily

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      25945547..25989816 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005621469.4 → XP_005621526.1  RNA exonuclease 5 isoform X1

      See identical proteins and their annotated locations for XP_005621526.1

      UniProtKB/TrEMBL
      A0A8C0PLF7, A0A8C0PNL5, A0A8I3N036, A0A8I3RTV6
      Conserved Domains (2) summary
      cd06145
      Location:230 → 378
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      cl17169
      Location:507 → 577
      RRM_SF; RNA recognition motif (RRM) superfamily

    2. XM_536947.6 → XP_536947.2  RNA exonuclease 5 isoform X1

      See identical proteins and their annotated locations for XP_536947.2

      UniProtKB/TrEMBL
      A0A8C0PLF7, A0A8C0PNL5, A0A8I3N036, A0A8I3RTV6
      Conserved Domains (2) summary
      cd06145
      Location:230 → 378
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      cl17169
      Location:507 → 577
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_005621467.4 → XP_005621524.1  RNA exonuclease 5 isoform X1

      See identical proteins and their annotated locations for XP_005621524.1

      UniProtKB/TrEMBL
      A0A8C0PLF7, A0A8C0PNL5, A0A8I3N036, A0A8I3RTV6
      Conserved Domains (2) summary
      cd06145
      Location:230 → 378
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      cl17169
      Location:507 → 577
      RRM_SF; RNA recognition motif (RRM) superfamily
    Nucleotide Protein
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