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    HTT huntingtin [ Canis lupus familiaris (dog) ]

    Gene ID: 479074, updated on 5-Mar-2024

    Summary

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    Official Symbol
    HTTprovided by VGNC
    Official Full Name
    huntingtinprovided by VGNC
    Primary source
    VGNC:VGNC:41839
    See related
    Ensembl:ENSCAFG00845011174
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    HD
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    67
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (61552532..61697091, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (63660661..63805148, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (61608204..61752888, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (61044140..61188581, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (61248468..61393186, complement)

    Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene HGF activator Neighboring gene regulator of G protein signaling 12 Neighboring gene Myb/SANT DNA binding domain containing 1 Neighboring gene G protein-coupled receptor kinase 4 Neighboring gene 40S ribosomal protein S15a-like Neighboring gene 40S ribosomal protein S16-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in microtubule-based transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    huntingtin
    Names
    huntingtin (Huntington disease)
    solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051807.1 Reference ROS_Cfam_1.0

      Range
      61552532..61697091 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038661694.1 → XP_038517622.1  huntingtin isoform X2

      UniProtKB/TrEMBL
      A0A8C0M2Z1, A0A8C0Q3X4
      Conserved Domains (2) summary
      sd00044
      Location:115 → 137
      HEAT; HEAT repeat [structural motif]
      pfam12372
      Location:1466 → 1506
      DUF3652; Huntingtin protein region

    2. XM_038661693.1 → XP_038517621.1  huntingtin isoform X1

      UniProtKB/TrEMBL
      A0A8C0M183
      Related
      ENSCAFP00845015538.1, ENSCAFT00845019844.1
      Conserved Domains (2) summary
      sd00044
      Location:115 → 137
      HEAT; HEAT repeat [structural motif]
      pfam12372
      Location:1503 → 1543
      DUF3652; Huntingtin protein region

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049263.1 Alternate UMICH_Zoey_3.1

      Range
      61044140..61188581 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038472221.1 → XP_038328149.1  huntingtin isoform X2

      Conserved Domains (2) summary
      sd00044
      Location:115 → 137
      HEAT; HEAT repeat [structural motif]
      pfam12372
      Location:1466 → 1506
      DUF3652; Huntingtin protein region

    2. XM_038472220.1 → XP_038328148.1  huntingtin isoform X1

      Conserved Domains (2) summary
      sd00044
      Location:115 → 137
      HEAT; HEAT repeat [structural motif]
      pfam12372
      Location:1503 → 1543
      DUF3652; Huntingtin protein region

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

      Range
      61248468..61393186 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038597511.1 → XP_038453439.1  huntingtin isoform X2

      Conserved Domains (2) summary
      sd00044
      Location:115 → 137
      HEAT; HEAT repeat [structural motif]
      pfam12372
      Location:1466 → 1506
      DUF3652; Huntingtin protein region

    2. XM_038597510.1 → XP_038453438.1  huntingtin isoform X1

      Conserved Domains (2) summary
      sd00044
      Location:115 → 137
      HEAT; HEAT repeat [structural motif]
      pfam12372
      Location:1503 → 1543
      DUF3652; Huntingtin protein region

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

      Range
      61608204..61752888 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038533184.1 → XP_038389112.1  huntingtin isoform X2

      UniProtKB/TrEMBL
      A0A8C0M2Z1, A0A8C0Q3X4
      Conserved Domains (2) summary
      sd00044
      Location:115 → 137
      HEAT; HEAT repeat [structural motif]
      pfam12372
      Location:1466 → 1506
      DUF3652; Huntingtin protein region

    2. XM_038533183.1 → XP_038389111.1  huntingtin isoform X1

      UniProtKB/TrEMBL
      A0A8C0M183
      Conserved Domains (2) summary
      sd00044
      Location:115 → 137
      HEAT; HEAT repeat [structural motif]
      pfam12372
      Location:1503 → 1543
      DUF3652; Huntingtin protein region

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      63660661..63805148 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014112541.3 → XP_013968016.1  huntingtin isoform X2

      UniProtKB/TrEMBL
      A0A8C0M2Z1, A0A8C0Q3X4
      Conserved Domains (2) summary
      sd00044
      Location:115 → 137
      HEAT; HEAT repeat [structural motif]
      pfam12372
      Location:1466 → 1506
      DUF3652; Huntingtin protein region

    2. XM_536221.6 → XP_536221.2  huntingtin isoform X1

      UniProtKB/TrEMBL
      A0A8C0M183
      Conserved Domains (2) summary
      sd00044
      Location:115 → 137
      HEAT; HEAT repeat [structural motif]
      pfam12372
      Location:1503 → 1543
      DUF3652; Huntingtin protein region
    Nucleotide Protein
    Heading Accession and Version

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