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    TRIP12 thyroid hormone receptor interactor 12 [ Canis lupus familiaris (dog) ]

    Gene ID: 477400, updated on 5-Mar-2024

    Summary

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    Official Symbol
    TRIP12provided by VGNC
    Official Full Name
    thyroid hormone receptor interactor 12provided by VGNC
    Primary source
    VGNC:VGNC:47845
    See related
    Ensembl:ENSCAFG00845018494
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See TRIP12 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    44
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (42314008..42461218, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (42683739..42830753, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (42259135..42406205, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (42245230..42392136, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (42085737..42233226, complement)

    Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene phosphotyrosine interaction domain containing 1 Neighboring gene uncharacterized LOC119865958 Neighboring gene histone-lysine N-methyltransferase SUV39H2-like Neighboring gene delta/notch like EGF repeat containing Neighboring gene F-box protein 36 Neighboring gene solute carrier family 16 member 14 Neighboring gene probable G-protein coupled receptor 148

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    probable E3 ubiquitin-protein ligase TRIP12; E3 ubiquitin-protein ligase TRIP12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051829.1 Reference ROS_Cfam_1.0

      Range
      42314008..42461218 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038435675.1 → XP_038291603.1  E3 ubiquitin-protein ligase TRIP12 isoform X8

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Conserved Domains (3) summary
      smart00119
      Location:1661 → 2029
      HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    2. XM_038435681.1 → XP_038291609.1  E3 ubiquitin-protein ligase TRIP12 isoform X14

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1596 → 1996
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 803
      WWE; WWE domain

    3. XM_038435677.1 → XP_038291605.1  E3 ubiquitin-protein ligase TRIP12 isoform X10

      UniProtKB/TrEMBL
      A0A8C0LB67
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1624 → 2024
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 831
      WWE; WWE domain

    4. XM_038435674.1 → XP_038291602.1  E3 ubiquitin-protein ligase TRIP12 isoform X7

      UniProtKB/TrEMBL
      A0A8C0LEL6, A0A8C0Z4L9
      Conserved Domains (3) summary
      COG5064
      Location:460 → 685
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1637 → 2037
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:782 → 844
      WWE; WWE domain

    5. XM_038435668.1 → XP_038291596.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LA96, A0A8C0LEY3, A0A8I3P6W4, A0A8P0T997
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    6. XM_038435665.1 → XP_038291593.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LA96, A0A8C0LEY3, A0A8I3P6W4, A0A8P0T997
      Related
      ENSCAFP00845025664.1, ENSCAFT00845032793.1
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    7. XM_038435667.1 → XP_038291595.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LA96, A0A8C0LEY3, A0A8I3P6W4, A0A8P0T997
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    8. XM_038435666.1 → XP_038291594.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LA96, A0A8C0LEY3, A0A8I3P6W4, A0A8P0T997
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    9. XM_038435680.1 → XP_038291608.1  E3 ubiquitin-protein ligase TRIP12 isoform X13

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1591 → 1991
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 803
      WWE; WWE domain

    10. XM_038435679.1 → XP_038291607.1  E3 ubiquitin-protein ligase TRIP12 isoform X12

      UniProtKB/TrEMBL
      A0A8C0LB67
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1618 → 2018
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 830
      WWE; WWE domain

    11. XM_038435678.1 → XP_038291606.1  E3 ubiquitin-protein ligase TRIP12 isoform X11

      UniProtKB/TrEMBL
      A0A8C0LB67, A0A8C0LFJ6, A0A8C0P954
      Related
      ENSCAFP00845026503.1, ENSCAFT00845033871.1
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1623 → 2023
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 830
      WWE; WWE domain

    12. XM_038435676.1 → XP_038291604.1  E3 ubiquitin-protein ligase TRIP12 isoform X9

      UniProtKB/TrEMBL
      A0A8C0LEL6, A0A8C0Z4L9
      Related
      ENSCAFP00845026755.1, ENSCAFT00845034176.1
      Conserved Domains (3) summary
      COG5064
      Location:460 → 685
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1631 → 2031
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:782 → 843
      WWE; WWE domain

    13. XM_038435673.1 → XP_038291601.1  E3 ubiquitin-protein ligase TRIP12 isoform X6

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Related
      ENSCAFP00845025822.1, ENSCAFT00845032996.1
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1638 → 2038
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 845
      WWE; WWE domain

    14. XM_038435671.1 → XP_038291599.1  E3 ubiquitin-protein ligase TRIP12 isoform X4

      UniProtKB/TrEMBL
      A0A8C0LEY3
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1660 → 2060
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 872
      WWE; WWE domain

    15. XM_038435669.1 → XP_038291597.1  E3 ubiquitin-protein ligase TRIP12 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LEY3, A0A8C0TGW8
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1665 → 2065
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 872
      WWE; WWE domain

    16. XM_038435672.1 → XP_038291600.1  E3 ubiquitin-protein ligase TRIP12 isoform X5

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1639 → 2039
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 846
      WWE; WWE domain

    17. XM_038435670.1 → XP_038291598.1  E3 ubiquitin-protein ligase TRIP12 isoform X3

      UniProtKB/TrEMBL
      A0A8C0LEY3
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1661 → 2061
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049285.1 Alternate UMICH_Zoey_3.1

      Range
      42245230..42392136 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038510606.1 → XP_038366534.1  E3 ubiquitin-protein ligase TRIP12 isoform X8

      Conserved Domains (3) summary
      smart00119
      Location:1661 → 2029
      HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    2. XM_038510612.1 → XP_038366540.1  E3 ubiquitin-protein ligase TRIP12 isoform X14

      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1596 → 1996
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 803
      WWE; WWE domain

    3. XM_038510608.1 → XP_038366536.1  E3 ubiquitin-protein ligase TRIP12 isoform X10

      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1624 → 2024
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 831
      WWE; WWE domain

    4. XM_038510605.1 → XP_038366533.1  E3 ubiquitin-protein ligase TRIP12 isoform X7

      Conserved Domains (3) summary
      COG5064
      Location:460 → 685
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1637 → 2037
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:782 → 844
      WWE; WWE domain

    5. XM_038510599.1 → XP_038366527.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    6. XM_038510596.1 → XP_038366524.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    7. XM_038510598.1 → XP_038366526.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    8. XM_038510597.1 → XP_038366525.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    9. XM_038510611.1 → XP_038366539.1  E3 ubiquitin-protein ligase TRIP12 isoform X13

      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1591 → 1991
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 803
      WWE; WWE domain

    10. XM_038510610.1 → XP_038366538.1  E3 ubiquitin-protein ligase TRIP12 isoform X12

      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1618 → 2018
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 830
      WWE; WWE domain

    11. XM_038510609.1 → XP_038366537.1  E3 ubiquitin-protein ligase TRIP12 isoform X11

      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1623 → 2023
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 830
      WWE; WWE domain

    12. XM_038510607.1 → XP_038366535.1  E3 ubiquitin-protein ligase TRIP12 isoform X9

      Conserved Domains (3) summary
      COG5064
      Location:460 → 685
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1631 → 2031
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:782 → 843
      WWE; WWE domain

    13. XM_038510604.1 → XP_038366532.1  E3 ubiquitin-protein ligase TRIP12 isoform X6

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1638 → 2038
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 845
      WWE; WWE domain

    14. XM_038510602.1 → XP_038366530.1  E3 ubiquitin-protein ligase TRIP12 isoform X4

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1660 → 2060
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 872
      WWE; WWE domain

    15. XM_038510600.1 → XP_038366528.1  E3 ubiquitin-protein ligase TRIP12 isoform X2

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1665 → 2065
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 872
      WWE; WWE domain

    16. XM_038510603.1 → XP_038366531.1  E3 ubiquitin-protein ligase TRIP12 isoform X5

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1639 → 2039
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 846
      WWE; WWE domain

    17. XM_038510601.1 → XP_038366529.1  E3 ubiquitin-protein ligase TRIP12 isoform X3

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1661 → 2061
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

      Range
      42085737..42233226 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038638384.1 → XP_038494312.1  E3 ubiquitin-protein ligase TRIP12 isoform X10

      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1624 → 2024
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 831
      WWE; WWE domain

    2. XM_038638381.1 → XP_038494309.1  E3 ubiquitin-protein ligase TRIP12 isoform X7

      Conserved Domains (3) summary
      COG5064
      Location:460 → 685
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1637 → 2037
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:782 → 844
      WWE; WWE domain

    3. XM_038638382.1 → XP_038494310.1  E3 ubiquitin-protein ligase TRIP12 isoform X8

      Conserved Domains (3) summary
      smart00119
      Location:1661 → 2029
      HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    4. XM_038638388.1 → XP_038494316.1  E3 ubiquitin-protein ligase TRIP12 isoform X14

      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1596 → 1996
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 803
      WWE; WWE domain

    5. XM_038638375.1 → XP_038494303.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    6. XM_038638372.1 → XP_038494300.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    7. XM_038638374.1 → XP_038494302.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    8. XM_038638373.1 → XP_038494301.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    9. XM_038638387.1 → XP_038494315.1  E3 ubiquitin-protein ligase TRIP12 isoform X13

      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1591 → 1991
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 803
      WWE; WWE domain

    10. XM_038638386.1 → XP_038494314.1  E3 ubiquitin-protein ligase TRIP12 isoform X12

      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1618 → 2018
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 830
      WWE; WWE domain

    11. XM_038638385.1 → XP_038494313.1  E3 ubiquitin-protein ligase TRIP12 isoform X11

      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1623 → 2023
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 830
      WWE; WWE domain

    12. XM_038638383.1 → XP_038494311.1  E3 ubiquitin-protein ligase TRIP12 isoform X9

      Conserved Domains (3) summary
      COG5064
      Location:460 → 685
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1631 → 2031
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:782 → 843
      WWE; WWE domain

    13. XM_038638380.1 → XP_038494308.1  E3 ubiquitin-protein ligase TRIP12 isoform X6

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1638 → 2038
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 845
      WWE; WWE domain

    14. XM_038638378.1 → XP_038494306.1  E3 ubiquitin-protein ligase TRIP12 isoform X4

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1660 → 2060
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 872
      WWE; WWE domain

    15. XM_038638376.1 → XP_038494304.1  E3 ubiquitin-protein ligase TRIP12 isoform X2

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1665 → 2065
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 872
      WWE; WWE domain

    16. XM_038638379.1 → XP_038494307.1  E3 ubiquitin-protein ligase TRIP12 isoform X5

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1639 → 2039
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 846
      WWE; WWE domain

    17. XM_038638377.1 → XP_038494305.1  E3 ubiquitin-protein ligase TRIP12 isoform X3

      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1661 → 2061
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

      Range
      42259135..42406205 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038574078.1 → XP_038430006.1  E3 ubiquitin-protein ligase TRIP12 isoform X8

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Conserved Domains (3) summary
      smart00119
      Location:1661 → 2029
      HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    2. XM_038574084.1 → XP_038430012.1  E3 ubiquitin-protein ligase TRIP12 isoform X14

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1596 → 1996
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 803
      WWE; WWE domain

    3. XM_038574080.1 → XP_038430008.1  E3 ubiquitin-protein ligase TRIP12 isoform X10

      UniProtKB/TrEMBL
      A0A8C0LB67
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1624 → 2024
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 831
      WWE; WWE domain

    4. XM_038574077.1 → XP_038430005.1  E3 ubiquitin-protein ligase TRIP12 isoform X7

      UniProtKB/TrEMBL
      A0A8C0LEL6, A0A8C0Z4L9
      Conserved Domains (3) summary
      COG5064
      Location:460 → 685
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1637 → 2037
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:782 → 844
      WWE; WWE domain

    5. XM_038574070.1 → XP_038429998.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LA96, A0A8C0LEY3, A0A8I3P6W4, A0A8P0T997
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    6. XM_038574067.1 → XP_038429995.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LA96, A0A8C0LEY3, A0A8I3P6W4, A0A8P0T997
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    7. XM_038574069.1 → XP_038429997.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LA96, A0A8C0LEY3, A0A8I3P6W4, A0A8P0T997
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    8. XM_038574068.1 → XP_038429996.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LA96, A0A8C0LEY3, A0A8I3P6W4, A0A8P0T997
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    9. XM_038574083.1 → XP_038430011.1  E3 ubiquitin-protein ligase TRIP12 isoform X13

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1591 → 1991
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 803
      WWE; WWE domain

    10. XM_038574082.1 → XP_038430010.1  E3 ubiquitin-protein ligase TRIP12 isoform X12

      UniProtKB/TrEMBL
      A0A8C0LB67
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1618 → 2018
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 830
      WWE; WWE domain

    11. XM_038574081.1 → XP_038430009.1  E3 ubiquitin-protein ligase TRIP12 isoform X11

      UniProtKB/TrEMBL
      A0A8C0LB67, A0A8C0LFJ6, A0A8C0P954
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1623 → 2023
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 830
      WWE; WWE domain

    12. XM_038574079.1 → XP_038430007.1  E3 ubiquitin-protein ligase TRIP12 isoform X9

      UniProtKB/TrEMBL
      A0A8C0LEL6, A0A8C0Z4L9
      Conserved Domains (3) summary
      COG5064
      Location:460 → 685
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1631 → 2031
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:782 → 843
      WWE; WWE domain

    13. XM_038574076.1 → XP_038430004.1  E3 ubiquitin-protein ligase TRIP12 isoform X6

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1638 → 2038
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 845
      WWE; WWE domain

    14. XM_038574073.1 → XP_038430001.1  E3 ubiquitin-protein ligase TRIP12 isoform X4

      UniProtKB/TrEMBL
      A0A8C0LEY3
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1660 → 2060
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 872
      WWE; WWE domain

    15. XM_038574071.1 → XP_038429999.1  E3 ubiquitin-protein ligase TRIP12 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LEY3, A0A8C0TGW8
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1665 → 2065
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 872
      WWE; WWE domain

    16. XM_038574075.1 → XP_038430003.1  E3 ubiquitin-protein ligase TRIP12 isoform X5

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1639 → 2039
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 846
      WWE; WWE domain

    17. XM_038574072.1 → XP_038430000.1  E3 ubiquitin-protein ligase TRIP12 isoform X3

      UniProtKB/TrEMBL
      A0A8C0LEY3
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1661 → 2061
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      42683739..42830753 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038458464.1 → XP_038314392.1  E3 ubiquitin-protein ligase TRIP12 isoform X8

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Conserved Domains (3) summary
      smart00119
      Location:1661 → 2029
      HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    2. XM_038458466.1 → XP_038314394.1  E3 ubiquitin-protein ligase TRIP12 isoform X14

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1596 → 1996
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 803
      WWE; WWE domain

    3. XM_038458465.1 → XP_038314393.1  E3 ubiquitin-protein ligase TRIP12 isoform X10

      UniProtKB/TrEMBL
      A0A8C0LB67
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1624 → 2024
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 831
      WWE; WWE domain

    4. XM_038458463.1 → XP_038314391.1  E3 ubiquitin-protein ligase TRIP12 isoform X7

      UniProtKB/TrEMBL
      A0A8C0LEL6, A0A8C0Z4L9
      Conserved Domains (3) summary
      COG5064
      Location:460 → 685
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1637 → 2037
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:782 → 844
      WWE; WWE domain

    5. XM_022409663.2 → XP_022265371.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LA96, A0A8C0LEY3, A0A8I3P6W4, A0A8P0T997
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    6. XM_038458460.1 → XP_038314388.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LA96, A0A8C0LEY3, A0A8I3P6W4, A0A8P0T997
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    7. XM_038458462.1 → XP_038314390.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LA96, A0A8C0LEY3, A0A8I3P6W4, A0A8P0T997
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    8. XM_038458461.1 → XP_038314389.1  E3 ubiquitin-protein ligase TRIP12 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LA96, A0A8C0LEY3, A0A8I3P6W4, A0A8P0T997
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1666 → 2066
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain

    9. XM_022409675.1 → XP_022265383.1  E3 ubiquitin-protein ligase TRIP12 isoform X13

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1591 → 1991
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 803
      WWE; WWE domain

    10. XM_022409674.1 → XP_022265382.1  E3 ubiquitin-protein ligase TRIP12 isoform X12

      UniProtKB/TrEMBL
      A0A8C0LB67
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1618 → 2018
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 830
      WWE; WWE domain

    11. XM_022409672.1 → XP_022265380.1  E3 ubiquitin-protein ligase TRIP12 isoform X11

      UniProtKB/TrEMBL
      A0A8C0LB67, A0A8C0LFJ6, A0A8C0P954
      Conserved Domains (4) summary
      PTZ00449
      Location:13 → 176
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG5064
      Location:447 → 672
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1623 → 2023
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:769 → 830
      WWE; WWE domain

    12. XM_022409671.1 → XP_022265379.1  E3 ubiquitin-protein ligase TRIP12 isoform X9

      UniProtKB/TrEMBL
      A0A8C0LEL6, A0A8C0Z4L9
      Conserved Domains (3) summary
      COG5064
      Location:460 → 685
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1631 → 2031
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:782 → 843
      WWE; WWE domain

    13. XM_022409668.1 → XP_022265376.1  E3 ubiquitin-protein ligase TRIP12 isoform X6

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1638 → 2038
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 845
      WWE; WWE domain

    14. XM_022409666.1 → XP_022265374.1  E3 ubiquitin-protein ligase TRIP12 isoform X4

      UniProtKB/TrEMBL
      A0A8C0LEY3
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1660 → 2060
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 872
      WWE; WWE domain

    15. XM_022409664.1 → XP_022265372.1  E3 ubiquitin-protein ligase TRIP12 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LEY3, A0A8C0TGW8
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1665 → 2065
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 872
      WWE; WWE domain

    16. XM_022409667.1 → XP_022265375.1  E3 ubiquitin-protein ligase TRIP12 isoform X5

      UniProtKB/TrEMBL
      A0A8I3NX09, A0A8P0P7Y2
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1639 → 2039
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 846
      WWE; WWE domain

    17. XM_022409665.1 → XP_022265373.1  E3 ubiquitin-protein ligase TRIP12 isoform X3

      UniProtKB/TrEMBL
      A0A8C0LEY3
      Conserved Domains (3) summary
      COG5064
      Location:489 → 714
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      cd00078
      Location:1661 → 2061
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:811 → 873
      WWE; WWE domain
    Nucleotide Protein
    Heading Accession and Version

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