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    KANK3 KN motif and ankyrin repeat domains 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 476723, updated on 5-Mar-2024

    Summary

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    Official Symbol
    KANK3provided by VGNC
    Official Full Name
    KN motif and ankyrin repeat domains 3provided by VGNC
    Primary source
    VGNC:VGNC:42202
    See related
    Ensembl:ENSCAFG00845005960
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    ANKRD47
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 20
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (53431281..53444168, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (52704716..52717589, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (53310788..53323647, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (52633748..52646584, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (53079221..53092071, complement)

    Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene NADH:ubiquinone oxidoreductase subunit A7 Neighboring gene ribosomal protein S28 Neighboring gene angiopoietin like 4 Neighboring gene uncharacterized LOC119864760 Neighboring gene RAB11B, member RAS oncogene family

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    KN motif and ankyrin repeat domain-containing protein 3; LOW QUALITY PROTEIN: KN motif and ankyrin repeat domain-containing protein 3
    Names
    ankyrin repeat domain 47

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051824.1 Reference ROS_Cfam_1.0

      Range
      53431281..53444168 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038428821.1 → XP_038284749.1  LOW QUALITY PROTEIN: KN motif and ankyrin repeat domain-containing protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LDQ1
      Related
      ENSCAFP00845008223.1, ENSCAFT00845010563.1
      Conserved Domains (5) summary
      PTZ00322
      Location:714 → 822
      PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
      PRK02224
      Location:196 → 367
      PRK02224; DNA double-strand break repair Rad50 ATPase
      COG0666
      Location:589 → 767
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:627 → 659
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:32 → 55
      KN_motif; KN motif

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049280.1 Alternate UMICH_Zoey_3.1

      Range
      52633748..52646584 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038504446.1 → XP_038360374.1  LOW QUALITY PROTEIN: KN motif and ankyrin repeat domain-containing protein 3 isoform X2

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

      Range
      53079221..53092071 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038631640.1 → XP_038487568.1  KN motif and ankyrin repeat domain-containing protein 3 isoform X3

    2. XM_038631641.1 → XP_038487569.1  KN motif and ankyrin repeat domain-containing protein 3 isoform X3

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

      Range
      53310788..53323647 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038567492.1 → XP_038423420.1  KN motif and ankyrin repeat domain-containing protein 3 isoform X4

      UniProtKB/TrEMBL
      A0A8C0LDQ1
      Conserved Domains (5) summary
      PTZ00322
      Location:711 → 819
      PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
      PRK02224
      Location:196 → 367
      PRK02224; DNA double-strand break repair Rad50 ATPase
      COG0666
      Location:586 → 764
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:624 → 656
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:32 → 55
      KN_motif; KN motif

    2. XM_038567493.1 → XP_038423421.1  KN motif and ankyrin repeat domain-containing protein 3 isoform X4

      UniProtKB/TrEMBL
      A0A8C0LDQ1
      Conserved Domains (5) summary
      PTZ00322
      Location:711 → 819
      PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
      PRK02224
      Location:196 → 367
      PRK02224; DNA double-strand break repair Rad50 ATPase
      COG0666
      Location:586 → 764
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:624 → 656
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:32 → 55
      KN_motif; KN motif

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      52704716..52717589 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_533927.7 → XP_533927.3  KN motif and ankyrin repeat domain-containing protein 3 isoform X5

      UniProtKB/TrEMBL
      A0A8C0LDQ1
      Conserved Domains (5) summary
      PTZ00322
      Location:711 → 819
      PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
      PRK02224
      Location:196 → 367
      PRK02224; DNA double-strand break repair Rad50 ATPase
      COG0666
      Location:586 → 764
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:624 → 656
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:32 → 55
      KN_motif; KN motif

    2. XM_038455092.1 → XP_038311020.1  KN motif and ankyrin repeat domain-containing protein 3 isoform X5

      UniProtKB/TrEMBL
      A0A8C0LDQ1
      Conserved Domains (5) summary
      PTZ00322
      Location:711 → 819
      PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
      PRK02224
      Location:196 → 367
      PRK02224; DNA double-strand break repair Rad50 ATPase
      COG0666
      Location:586 → 764
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:624 → 656
      ANK; ANK repeat [structural motif]
      pfam12075
      Location:32 → 55
      KN_motif; KN motif
    Nucleotide Protein
    Heading Accession and Version

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