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    DNAH1 dynein axonemal heavy chain 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 476598, updated on 5-Mar-2024

    Summary

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    Official Symbol
    DNAH1provided by VGNC
    Official Full Name
    dynein axonemal heavy chain 1provided by VGNC
    Primary source
    VGNC:VGNC:40011
    See related
    Ensembl:ENSCAFG00845030603
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 20
    Exon count:
    78
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (37714963..37791616, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (37346392..37423030, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (37772261..37848897, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (37078913..37155548, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (37487581..37564217, complement)

    Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene PHD finger protein 7 Neighboring gene BRCA1 associated protein 1 Neighboring gene microRNA mir-135a-1 Neighboring gene glycerate kinase Neighboring gene microRNA let-7g Neighboring gene WD repeat domain 82

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables dynein intermediate chain binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables dynein light intermediate chain binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables minus-end-directed microtubule motor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of dynein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dynein heavy chain 1, axonemal

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051824.1 Reference ROS_Cfam_1.0

      Range
      37714963..37791616 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038427564.1 → XP_038283492.1  dynein heavy chain 1, axonemal

      UniProtKB/TrEMBL
      A0A8C0MUW8, A0A8C0TFS5, A0A8I3QA04
      Related
      ENSCAFP00845042667.1, ENSCAFT00845054305.1
      Conserved Domains (4) summary
      COG5245
      Location:1255 → 3905
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:1016 → 1419
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1546 → 1872
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam18199
      Location:3962 → 4264
      Dynein_C; Dynein heavy chain C-terminal domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049280.1 Alternate UMICH_Zoey_3.1

      Range
      37078913..37155548 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038503281.1 → XP_038359209.1  dynein heavy chain 1, axonemal

      Conserved Domains (4) summary
      COG5245
      Location:1255 → 3905
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:1016 → 1419
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1546 → 1872
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam18199
      Location:3962 → 4264
      Dynein_C; Dynein heavy chain C-terminal domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

      Range
      37487581..37564217 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038630418.1 → XP_038486346.1  dynein heavy chain 1, axonemal

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

      Range
      37772261..37848897 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038566258.1 → XP_038422186.1  dynein heavy chain 1, axonemal

      UniProtKB/TrEMBL
      A0A8C0MUW8, A0A8C0TFS5, A0A8I3QA04
      Conserved Domains (4) summary
      COG5245
      Location:1255 → 3905
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:1016 → 1419
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1546 → 1872
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam18199
      Location:3962 → 4264
      Dynein_C; Dynein heavy chain C-terminal domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      37346392..37423030 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022406641.2 → XP_022262349.1  dynein heavy chain 1, axonemal

      UniProtKB/TrEMBL
      A0A8C0MUW8, A0A8C0TFS5, A0A8I3QA04
      Conserved Domains (4) summary
      COG5245
      Location:1255 → 3905
      DYN1; Dynein, heavy chain [Cytoskeleton]
      pfam08393
      Location:1016 → 1419
      DHC_N2; Dynein heavy chain, N-terminal region 2
      pfam12774
      Location:1546 → 1872
      AAA_6; Hydrolytic ATP binding site of dynein motor region D1
      pfam18199
      Location:3962 → 4264
      Dynein_C; Dynein heavy chain C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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