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    ACVR2A activin A receptor type 2A [ Canis lupus familiaris (dog) ]

    Gene ID: 476140, updated on 5-Mar-2024

    Summary

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    Official Symbol
    ACVR2Aprovided by VGNC
    Official Full Name
    activin A receptor type 2Aprovided by VGNC
    Primary source
    VGNC:VGNC:37564
    See related
    Ensembl:ENSCAFG00845006266
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ACVR2A in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 19 NC_051823.1 (51114507..51199229)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 19 NC_006601.4 (49765961..49850433)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 19 NC_049240.1 (51291788..51376557)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 19 NC_049279.1 (49760723..49845201)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 19 NC_049760.1 (49894649..49979187)

    Chromosome 19 - NC_051823.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111091197 Neighboring gene 60S ribosomal protein L26-like Neighboring gene phosphate carrier protein, mitochondrial-like Neighboring gene origin recognition complex subunit 4 Neighboring gene uncharacterized LOC119864497

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables activin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables activin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activin receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of activin receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    activin receptor type-2A
    XP_038282146.1
    XP_038282147.1
    XP_038310617.1
    XP_038358340.1
    XP_038358341.1
    XP_038421063.1
    XP_038421064.1
    XP_038485161.1
    XP_038485163.1
    XP_857260.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051823.1 Reference ROS_Cfam_1.0

      Range
      51114507..51199229
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038426218.1 → XP_038282146.1  activin receptor type-2A isoform X1

      UniProtKB/TrEMBL
      A0A8C0R225, A0A8C0Z3E6, A0A8I3MYH0
      Related
      ENSCAFP00845008741.1, ENSCAFT00845011205.1
      Conserved Domains (2) summary
      cd14141
      Location:196 → 485
      STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor
      pfam01064
      Location:59 → 111
      Activin_recp; Activin types I and II receptor domain

    2. XM_038426219.1 → XP_038282147.1  activin receptor type-2A isoform X2

      Conserved Domains (1) summary
      cd14141
      Location:88 → 377
      STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049279.1 Alternate UMICH_Zoey_3.1

      Range
      49760723..49845201
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038502412.1 → XP_038358340.1  activin receptor type-2A isoform X1

      Conserved Domains (2) summary
      cd14141
      Location:196 → 485
      STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor
      pfam01064
      Location:59 → 111
      Activin_recp; Activin types I and II receptor domain

    2. XM_038502413.1 → XP_038358341.1  activin receptor type-2A isoform X2

      Conserved Domains (1) summary
      cd14141
      Location:88 → 377
      STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049760.1 Alternate UNSW_CanFamBas_1.0

      Range
      49894649..49979187
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038629233.1 → XP_038485161.1  activin receptor type-2A isoform X1

      Conserved Domains (2) summary
      cd14141
      Location:196 → 485
      STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor
      pfam01064
      Location:59 → 111
      Activin_recp; Activin types I and II receptor domain

    2. XM_038629235.1 → XP_038485163.1  activin receptor type-2A isoform X2

      Conserved Domains (1) summary
      cd14141
      Location:88 → 377
      STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049240.1 Alternate UU_Cfam_GSD_1.0

      Range
      51291788..51376557
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038565135.1 → XP_038421063.1  activin receptor type-2A isoform X1

      UniProtKB/TrEMBL
      A0A8C0R225, A0A8C0Z3E6, A0A8I3MYH0
      Conserved Domains (2) summary
      cd14141
      Location:196 → 485
      STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor
      pfam01064
      Location:59 → 111
      Activin_recp; Activin types I and II receptor domain

    2. XM_038565136.1 → XP_038421064.1  activin receptor type-2A isoform X2

      Conserved Domains (1) summary
      cd14141
      Location:88 → 377
      STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006601.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      49765961..49850433
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_852167.6 → XP_857260.1  activin receptor type-2A isoform X1

      See identical proteins and their annotated locations for XP_857260.1

      UniProtKB/TrEMBL
      A0A8C0R225, A0A8C0Z3E6, A0A8I3MYH0
      Conserved Domains (2) summary
      cd14141
      Location:196 → 485
      STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor
      pfam01064
      Location:59 → 111
      Activin_recp; Activin types I and II receptor domain

    2. XM_038454689.1 → XP_038310617.1  activin receptor type-2A isoform X2

      Conserved Domains (1) summary
      cd14141
      Location:88 → 377
      STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor
    Nucleotide Protein
    Heading Accession and Version

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