CS citrate synthase [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: CSprovided by VGNC
Official Full Name: citrate synthaseprovided by VGNC
Primary source: VGNC:VGNC:49800
See related: Ensembl:ENSCAFG00845007644
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	10	NC_051814.1 (592484..620012, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	10	NC_006592.4 (647257..674790, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	10	NC_049231.1 (937007..964321, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	10	NC_049270.1 (569926..597448, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	10	NC_049751.1 (812910..840419, complement)

Chromosome 10 - NC_051814.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables citrate (Si)-synthase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in citrate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in tricarboxylic acid cycle	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrial matrix	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: citrate synthase, mitochondrial

Names: canopy 2 homolog

XP_022279760.1

EC 2.3.3.1

XP_038343710.1

EC 2.3.3.1

XP_038343711.1

EC 2.3.3.1

XP_038405600.1

EC 2.3.3.1

XP_038405601.1

EC 2.3.3.1

XP_038469566.1

EC 2.3.3.1

XP_038469567.1

EC 2.3.3.1

XP_038534931.1

EC 2.3.3.1

XP_038534932.1

EC 2.3.3.1

XP_531634.2

EC 2.3.3.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051814.1 Reference ROS_Cfam_1.0

Range

592484..620012 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038679003.1 → XP_038534931.1 citrate synthase, mitochondrial isoform X1

UniProtKB/TrEMBL

A0A8C0Q4T7, A0A8C0QGS7, A0A8I3N305, A0A8I3RVM2

Related

ENSCAFP00845010689.1, ENSCAFT00845013771.1

Conserved Domains (1) summary

cd06105
Location:33 → 459

ScCit1-2_like; Saccharomyces cerevisiae (Sc) citrate synthases Cit1-2_like. Citrate synthases (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) with oxaloacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or ...
XM_038679004.1 → XP_038534932.1 citrate synthase, mitochondrial isoform X2

UniProtKB/TrEMBL

A0A8C0Q4T7, A0A8I3N305

Related

ENSCAFP00845010719.1, ENSCAFT00845013817.1

Conserved Domains (1) summary

cd06105
Location:26 → 452

ScCit1-2_like; Saccharomyces cerevisiae (Sc) citrate synthases Cit1-2_like. Citrate synthases (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) with oxaloacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049270.1 Alternate UMICH_Zoey_3.1

Range

569926..597448 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038487782.1 → XP_038343710.1 citrate synthase, mitochondrial isoform X1

Conserved Domains (1) summary

cd06105
Location:33 → 459

ScCit1-2_like; Saccharomyces cerevisiae (Sc) citrate synthases Cit1-2_like. Citrate synthases (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) with oxaloacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or ...
XM_038487783.1 → XP_038343711.1 citrate synthase, mitochondrial isoform X2

Conserved Domains (1) summary

cd06105
Location:26 → 452

ScCit1-2_like; Saccharomyces cerevisiae (Sc) citrate synthases Cit1-2_like. Citrate synthases (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) with oxaloacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049751.1 Alternate UNSW_CanFamBas_1.0

Range

812910..840419 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038613638.1 → XP_038469566.1 citrate synthase, mitochondrial isoform X1

Conserved Domains (1) summary

cd06105
Location:33 → 459

ScCit1-2_like; Saccharomyces cerevisiae (Sc) citrate synthases Cit1-2_like. Citrate synthases (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) with oxaloacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or ...
XM_038613639.1 → XP_038469567.1 citrate synthase, mitochondrial isoform X2

Conserved Domains (1) summary

cd06105
Location:26 → 452

ScCit1-2_like; Saccharomyces cerevisiae (Sc) citrate synthases Cit1-2_like. Citrate synthases (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) with oxaloacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049231.1 Alternate UU_Cfam_GSD_1.0

Range

937007..964321 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038549672.1 → XP_038405600.1 citrate synthase, mitochondrial isoform X1

UniProtKB/TrEMBL

A0A8C0Q4T7, A0A8C0QGS7, A0A8I3N305, A0A8I3RVM2

Conserved Domains (1) summary

cd06105
Location:33 → 459

ScCit1-2_like; Saccharomyces cerevisiae (Sc) citrate synthases Cit1-2_like. Citrate synthases (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) with oxaloacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or ...
XM_038549673.1 → XP_038405601.1 citrate synthase, mitochondrial isoform X2

UniProtKB/TrEMBL

A0A8C0Q4T7, A0A8I3N305

Conserved Domains (1) summary

cd06105
Location:26 → 452

ScCit1-2_like; Saccharomyces cerevisiae (Sc) citrate synthases Cit1-2_like. Citrate synthases (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) with oxaloacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

647257..674790 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_531634.7 → XP_531634.2 citrate synthase, mitochondrial isoform X1

See identical proteins and their annotated locations for XP_531634.2

UniProtKB/TrEMBL

A0A8C0Q4T7, A0A8C0QGS7, A0A8I3N305, A0A8I3RVM2

Conserved Domains (1) summary

cd06105
Location:33 → 459

ScCit1-2_like; Saccharomyces cerevisiae (Sc) citrate synthases Cit1-2_like. Citrate synthases (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) with oxaloacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or ...
XM_022424052.2 → XP_022279760.1 citrate synthase, mitochondrial isoform X2

UniProtKB/TrEMBL

A0A8C0Q4T7, A0A8I3N305

Conserved Domains (1) summary

cd06105
Location:26 → 452

ScCit1-2_like; Saccharomyces cerevisiae (Sc) citrate synthases Cit1-2_like. Citrate synthases (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) with oxaloacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or ...