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    LIN7C lin-7 homolog C, crumbs cell polarity complex component [ Pan troglodytes (chimpanzee) ]

    Gene ID: 466475, updated on 29-Mar-2024

    Summary

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    Official Symbol
    LIN7Cprovided by VGNC
    Official Full Name
    lin-7 homolog C, crumbs cell polarity complex componentprovided by VGNC
    Primary source
    VGNC:VGNC:7759
    Locus tag
    CK820_G0005530
    See related
    Ensembl:ENSPTRG00000003457
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 9 NC_072407.2 (31498067..31510242, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 11 NC_072409.1 (31360057..31372392, complement)

    Chromosome 9 - NC_072407.2Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing G protein-coupled receptor 4 Neighboring gene large ribosomal subunit protein eL43-like Neighboring gene uncharacterized LOC104008451 Neighboring gene small ribosomal subunit protein eS25-like Neighboring gene uncharacterized LOC134807337

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables L27 domain binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in maintenance of epithelial cell apical/basal polarity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neurotransmitter secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to basolateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MPP7-DLG1-LIN7 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in basolateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cell-cell junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein lin-7 homolog C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      31498067..31510242 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054661271.2 → XP_054517246.1  protein lin-7 homolog C isoform X2

    2. XM_521874.8 → XP_521874.2  protein lin-7 homolog C isoform X1

      See identical proteins and their annotated locations for XP_521874.2

      UniProtKB/TrEMBL
      A0A2J8P4E9, A0A6D2WLJ8, H2R0V3
      Related
      ENSPTRP00000041313.3
      Conserved Domains (2) summary
      cd00992
      Location:91 → 172
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02828
      Location:14 → 66
      L27; L27 domain
    Nucleotide Protein
    Heading Accession and Version

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