LAP3 leucine aminopeptidase 3 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: LAP3provided by VGNC
Official Full Name: leucine aminopeptidase 3provided by VGNC
Primary source: VGNC:VGNC:625
Locus tag: CK820_G0007649
See related: Ensembl:ENSPTRG00000015938
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	3	NC_072401.2 (18061092..18091902)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	4	NC_072402.1 (18061242..18091885)

Chromosome 3 - NC_072401.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SHGC-59685 (e-PCR)
- UniSTS:13074

SHGC-24779 (e-PCR)
- UniSTS:48151

LAP3__6369 (e-PCR)
- UniSTS:464034

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables manganese ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables metalloaminopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: cytosol aminopeptidase

NP_001233394.1

EC 3.4.11.1

EC 3.4.11.5

EC 3.4.13.23

XP_016806458.1

EC 3.4.11.1

EC 3.4.11.5

EC 3.4.13.23

XP_063664027.1

EC 3.4.11.1

EC 3.4.11.5

EC 3.4.13.23

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001246465.1 → NP_001233394.1 cytosol aminopeptidase

See identical proteins and their annotated locations for NP_001233394.1

Status: PROVISIONAL

Source sequence(s)

AK306160

UniProtKB/TrEMBL

A0A2J8NW96, A0A2J8NW98, A0A6D2XVP4, G2HHE6

Related

ENSPTRP00000027448.2, ENSPTRT00000029748.3

Conserved Domains (1) summary

cd00433
Location:33 → 511

Peptidase_M17; Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and ...

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072401.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

18061092..18091902

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063807957.1 → XP_063664027.1 cytosol aminopeptidase isoform X1
XM_016950969.3 → XP_016806458.1 cytosol aminopeptidase isoform X2

UniProtKB/TrEMBL

A0A2J8NW96