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    PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing [ Pan troglodytes (chimpanzee) ]

    Gene ID: 459908, updated on 3-Apr-2024

    Summary

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    Official Symbol
    PIKFYVEprovided by VGNC
    Official Full Name
    phosphoinositide kinase, FYVE-type zinc finger containingprovided by VGNC
    Primary source
    VGNC:VGNC:2754
    Locus tag
    CK820_G0014999
    See related
    Ensembl:ENSPTRG00000012866
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Also known as
    PIP5K3
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2B
    Exon count:
    44
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 13 NC_072411.2 (110499830..110592440)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2B NC_072400.1 (110410987..110503598)

    Chromosome 13 - NC_072411.2Genomic Context describing neighboring genes Neighboring gene chromosome 13 C2orf80 homolog Neighboring gene isocitrate dehydrogenase (NADP(+)) 1 Neighboring gene parathyroid hormone 2 receptor Neighboring gene uncharacterized LOC134808004

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-phosphate 5-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables 1-phosphatidylinositol-5-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in melanosome organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neutrophil chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phagosome-lysosome fusion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of reactive oxygen species biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1-phosphatidylinositol 3-phosphate 5-kinase
    Names
    phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III
    phosphoinositide kinase, FYVE finger containing
    XP_009442403.2
    XP_009442405.2
    XP_009442406.2
    XP_009442407.2
    XP_009442408.2
    XP_009442409.2
    XP_009442410.2
    XP_009442411.2
    XP_009442412.2
    XP_009442413.2
    XP_009442414.2
    XP_009442415.2
    XP_009442416.2
    XP_009442419.1
    XP_016805884.2
    XP_054535242.1
    XP_054535243.1
    XP_054535244.1
    XP_063646773.1
    XP_063646774.1
    XP_063646775.1
    XP_063646776.1
    XP_063646777.1
    XP_063646778.1
    XP_063646779.1
    XP_063646780.1
    XP_063646781.1
    XP_063646782.1
    XP_516057.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      110499830..110592440
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_516057.8 → XP_516057.3  1-phosphatidylinositol 3-phosphate 5-kinase isoform X4

      UniProtKB/TrEMBL
      K7BNI2

    2. XM_054679268.2 → XP_054535243.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X12

    3. XM_009444140.5 → XP_009442415.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X16

    4. XM_009444144.3 → XP_009442419.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X24

      See identical proteins and their annotated locations for XP_009442419.1

      UniProtKB/TrEMBL
      A0A2I3RHI3, A0A2I3TVU9, A0A2J8N5Y7, A0A2J8N5Y8, A0A6D2W211, A0A6D2WV41
      Related
      ENSPTRP00000064097.1
      Conserved Domains (1) summary
      cd04448
      Location:260 → 341
      DEP_PIKfyve; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in fungal RhoGEF (GDP/GTP exchange factor) PIKfyve-like proteins. PIKfyve contains N-terminal Fyve finger and DEP domains, a central chaperonin-like domain and a C-terminal PIPK (phosphatidylinositol ...

    5. XM_054679267.2 → XP_054535242.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X5

    6. XM_063790703.1 → XP_063646773.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X13

    7. XM_009444128.5 → XP_009442403.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X1

    8. XM_009444133.5 → XP_009442408.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X7

    9. XM_009444136.5 → XP_009442411.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X10

    10. XM_009444132.5 → XP_009442407.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X6

    11. XM_009444134.5 → XP_009442409.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X8

    12. XM_009444131.5 → XP_009442406.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X3

    13. XM_009444137.5 → XP_009442412.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X11

    14. XM_009444138.5 → XP_009442413.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X14

    15. XM_009444130.5 → XP_009442405.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X2

    16. XM_009444135.5 → XP_009442410.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X9

    17. XM_009444139.5 → XP_009442414.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X15

    18. XM_009444141.5 → XP_009442416.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X18

    19. XM_054679269.2 → XP_054535244.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X19

    20. XM_063790707.1 → XP_063646777.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X20

    21. XM_063790711.1 → XP_063646781.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X23

    22. XM_063790709.1 → XP_063646779.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X21

    23. XM_063790705.1 → XP_063646775.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X20

    24. XM_063790704.1 → XP_063646774.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X20

    25. XM_063790708.1 → XP_063646778.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X20

    26. XM_063790712.1 → XP_063646782.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X23

    27. XM_016950395.4 → XP_016805884.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X17

    28. XM_063790706.1 → XP_063646776.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X20

    29. XM_063790710.1 → XP_063646780.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X22

    RNA

    1. XR_678623.5 RNA Sequence

    2. XR_010149859.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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