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    SIRPA signal regulatory protein alpha [ Pan troglodytes (chimpanzee) ]

    Gene ID: 458039, updated on 3-Apr-2024

    Summary

    Official Symbol
    SIRPAprovided by VGNC
    Official Full Name
    signal regulatory protein alphaprovided by VGNC
    Primary source
    VGNC:VGNC:54155
    Locus tag
    CK820_G0017434
    See related
    Ensembl:ENSPTRG00000013171
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
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    Genomic context

    Location:
    chromosome: 20
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 21 NC_072419.2 (8528932..8574571)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 20 NC_072418.1 (2063525..2109056, complement)

    Chromosome 21 - NC_072419.2Genomic Context describing neighboring genes Neighboring gene signal-regulatory protein beta-1 Neighboring gene signal regulatory protein gamma Neighboring gene uncharacterized LOC134809210 Neighboring gene uncharacterized LOC107969908 Neighboring gene prodynorphin

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in positive regulation of T cell activation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in positive regulation of phagocytosis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    tyrosine-protein phosphatase non-receptor type substrate 1
    XP_016792802.1
    XP_016792804.1
    XP_054530387.1
    XP_054530389.1
    XP_063659376.1
    XP_063659377.1
    XP_063659378.1
    XP_063659379.1
    XP_063659380.1
    XP_063659381.1
    XP_063659382.1
    XP_063659383.1
    XP_063659384.1
    XP_063659385.1
    XP_063659386.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072419.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      8528932..8574571
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_016937315.4XP_016792804.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X3

      UniProtKB/TrEMBL
      A0A2J8MS28, A0A6D2XF74, H2R958, K7BGA6, K7C2V5
      Related
      ENSPTRP00000052461.4
      Conserved Domains (3) summary
      cd05772
      Location:147250
      IgC_SIRP_domain_2; Signal-regulatory protein (SIRP) immunoglobulin-like domain 2
      cd16085
      Location:252355
      IgC_SIRP_domain_3; Signal-regulatory protein (SIRP) immunoglobulin-like domain 3
      cd16097
      Location:35145
      IgV_SIRP; Immunoglobulin (Ig)-like domain of Signal-Regulatory Protein (SIRP)
    2. XM_063803315.1XP_063659385.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X10

    3. XM_063803313.1XP_063659383.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X7

    4. XM_063803308.1XP_063659378.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X3

      UniProtKB/TrEMBL
      A0A2J8MS28, A0A6D2XF74, H2R958, K7BGA6
    5. XM_063803306.1XP_063659376.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X1

      UniProtKB/TrEMBL
      A0A2J8MS31, A0A803KK59, K7DU03
    6. XM_063803311.1XP_063659381.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X4

    7. XM_063803316.1XP_063659386.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X10

    8. XM_063803314.1XP_063659384.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X9

    9. XM_054674412.2XP_054530387.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X6

    10. XM_063803309.1XP_063659379.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X3

      UniProtKB/TrEMBL
      A0A2J8MS28, A0A6D2XF74, H2R958, K7BGA6
    11. XM_063803310.1XP_063659380.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X4

    12. XM_016937313.4XP_016792802.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X1

      UniProtKB/TrEMBL
      A0A2J8MS31, A0A803KK59, K7C8U8, K7DU03
      Related
      ENSPTRP00000067481.1
      Conserved Domains (3) summary
      cd05772
      Location:147250
      IgC_SIRP_domain_2; Signal-regulatory protein (SIRP) immunoglobulin-like domain 2
      cd16085
      Location:252355
      IgC_SIRP_domain_3; Signal-regulatory protein (SIRP) immunoglobulin-like domain 3
      cd16097
      Location:35145
      IgV_SIRP; Immunoglobulin (Ig)-like domain of Signal-Regulatory Protein (SIRP)
    13. XM_054674414.2XP_054530389.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X8

    14. XM_063803307.1XP_063659377.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X2

    15. XM_063803312.1XP_063659382.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X5