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    GPR137B G protein-coupled receptor 137B [ Pan troglodytes (chimpanzee) ]

    Gene ID: 457840, updated on 29-Mar-2024

    Summary

    Official Symbol
    GPR137Bprovided by VGNC
    Official Full Name
    G protein-coupled receptor 137Bprovided by VGNC
    Primary source
    VGNC:VGNC:8041
    Locus tag
    CK820_G0023207
    See related
    Ensembl:ENSPTRG00000002136
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    Location:
    chromosome: 1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (12958058..13024738, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (218298688..218365280)

    Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene peptidyl-prolyl cis-trans isomerase FKBP3-like Neighboring gene U2 spliceosomal RNA Neighboring gene endoplasmic reticulum oxidoreductase 1 beta Neighboring gene aconitate hydratase, mitochondrial-like Neighboring gene nidogen 1

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in negative regulation of bone resorption IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in negative regulation of osteoclast differentiation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in positive regulation of TORC1 signaling IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of autophagy IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    integral membrane protein GPR137B
    Names
    transmembrane 7 superfamily member 1 (upregulated in kidney)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      12958058..13024738 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_514290.9XP_514290.2  integral membrane protein GPR137B isoform X1

      See identical proteins and their annotated locations for XP_514290.2

      UniProtKB/TrEMBL
      A0A2J8M6U8, A0A6D2WP05, H2Q1E1
      Related
      ENSPTRP00000003608.3
      Conserved Domains (1) summary
      cd21476
      Location:35354
      7tm_GPR137B; Integral membrane protein GPR137B, an orphan receptor member of the seven-transmembrane G protein-coupled receptor superfamily
    2. XM_009441710.5XP_009439985.1  integral membrane protein GPR137B isoform X3

      See identical proteins and their annotated locations for XP_009439985.1

      UniProtKB/TrEMBL
      A0A2J8M6V0
      Conserved Domains (2) summary
      cd21464
      Location:4668
      7tm_GPR137; TM helix 1 [structural motif]
      cl28897
      Location:35322
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    3. XM_009441709.5XP_009439984.1  integral membrane protein GPR137B isoform X2

      UniProtKB/TrEMBL
      A0A2J8M6V0