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    PRDX1 peroxiredoxin 1 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 456537, updated on 3-Apr-2024

    Summary

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    Official Symbol
    PRDX1provided by VGNC
    Official Full Name
    peroxiredoxin 1provided by VGNC
    Primary source
    VGNC:VGNC:1469
    Locus tag
    CK820_G0025630
    See related
    Ensembl:ENSPTRG00000000675
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (185443513..185455362)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (45843940..45855790, complement)

    Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene nuclear autoantigenic sperm protein Neighboring gene aldo-keto reductase family 1 member A1 Neighboring gene metabolism of cobalamin associated C Neighboring gene CCDC163 homolog Neighboring gene UPF0764 protein C16orf89-like Neighboring gene testis associated actin remodelling kinase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables thioredoxin peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell redox homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hydrogen peroxide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in leukocyte activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in removal of superoxide radicals IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    peroxiredoxin-1
    XP_001156568.1
    XP_003308110.1
    XP_016817283.1
    XP_054538589.1
    XP_054538591.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      185443513..185455362
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001156568.8 → XP_001156568.1  peroxiredoxin-1

      See identical proteins and their annotated locations for XP_001156568.1

      UniProtKB/TrEMBL
      A0A2J8M026, A0A2J8M081, A0A6D2WW41, H2PYX4
      Conserved Domains (1) summary
      cd03015
      Location:8 → 180
      PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...

    2. XM_003308062.7 → XP_003308110.1  peroxiredoxin-1

      See identical proteins and their annotated locations for XP_003308110.1

      UniProtKB/TrEMBL
      A0A2J8M026, A0A2J8M081, A0A6D2WW41, H2PYX4
      Conserved Domains (1) summary
      cd03015
      Location:8 → 180
      PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...

    3. XM_054682614.2 → XP_054538589.1  peroxiredoxin-1

      UniProtKB/TrEMBL
      A0A2J8M026, A0A6D2WW41, H2PYX4

    4. XM_016961794.4 → XP_016817283.1  peroxiredoxin-1

      UniProtKB/TrEMBL
      A0A2J8M026, A0A2J8M081, A0A6D2WW41, H2PYX4
      Related
      ENSPTRP00000001167.4
      Conserved Domains (1) summary
      cd03015
      Location:8 → 180
      PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...

    5. XM_054682616.2 → XP_054538591.1  peroxiredoxin-1

      UniProtKB/TrEMBL
      A0A2J8M026, A0A6D2WW41, H2PYX4
    Nucleotide Protein
    Heading Accession and Version

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