KPNA3 karyopherin subunit alpha 3 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: KPNA3provided by VGNC
Official Full Name: karyopherin subunit alpha 3provided by VGNC
Primary source: VGNC:VGNC:7293
Locus tag: CK820_G0031619
See related: Ensembl:ENSPTRG00000005878
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	14	NC_072412.2 (55293372..55386201, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	13	NC_072411.1 (50660242..50753073, complement)

Chromosome 14 - NC_072412.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

EST9H12 (e-PCR)
- UniSTS:263444

G43604 (e-PCR)
- UniSTS:95039

SHGC-2160 (e-PCR)
- UniSTS:86113

D13S663E (e-PCR)
- UniSTS:153194

RH103323 (e-PCR)
- UniSTS:97654

MARC_17027-17028:1023293711:3 (e-PCR)
- UniSTS:268189

MARC_17027-17028:1032295869:3 (e-PCR)
- UniSTS:268189

D13S862E (e-PCR)
- UniSTS:64419

D13S825E (e-PCR)
- UniSTS:151502

KPNA3 (e-PCR)
- UniSTS:505312

KPNA3_1525 (e-PCR)
- UniSTS:462306

KPNA3_v515 (e-PCR)
- UniSTS:462306

D13S273 (e-PCR), detects polymorphism
- UniSTS:39164

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables nuclear import signal receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables nuclear localization sequence binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in NLS-bearing protein import into nucleus	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: importin subunit alpha-4

Names: karyopherin alpha 3 (importin alpha 4)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072412.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

55293372..55386201 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016925292.4 → XP_016780781.1 importin subunit alpha-4 isoform X1

UniProtKB/TrEMBL

A0A2I3RKC3, A0A2J8L8Q7, A0A6D2XXA7, H2Q7K7

Related

ENSPTRP00000010000.3

Conserved Domains (2) summary

COG5064
Location:2 → 521

SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]

sd00043
Location:109 → 142

ARM; armadillo repeat [structural motif]
XM_009426958.5 → XP_009425233.2 importin subunit alpha-4 isoform X2

UniProtKB/TrEMBL

A0A2I3RKC3

Related

ENSPTRP00000065117.1

Conserved Domains (2) summary

COG5064
Location:1 → 497

SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]

sd00043
Location:85 → 118

ARM; armadillo repeat [structural motif]