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    Ppp1ccb protein phosphatase 1 catalytic subunit gamma B [ Mus musculus (house mouse) ]

    Gene ID: 434233, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Ppp1ccbprovided by MGI
    Official Full Name
    protein phosphatase 1 catalytic subunit gamma Bprovided by MGI
    Primary source
    MGI:MGI:3647492
    See related
    Ensembl:ENSMUSG00000121724 AllianceGenome:MGI:3647492
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PP-1G; Gm5601; Ppp1cc; EG434233
    Summary
    Orthologous to human PPP1CC (protein phosphatase 1 catalytic subunit gamma). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 282.6), CNS E11.5 (RPKM 102.0) and 25 other tissues See more
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    Genomic context

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    Location:
    7 F2; 7 64.15 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (119339133..119341467)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (119739910..119742244)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene THUMP domain containing 1 Neighboring gene predicted gene, 39080 Neighboring gene UPF0124 protein C13orf31 homolog Neighboring gene acyl-CoA synthetase medium-chain family member 3 Neighboring gene predicted gene, 57786

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis. Mikula M, et al. Proteome Sci, 2015. PMID 26336360, Free PMC Article
    2. Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization. Watkins DS, et al. Proteomes, 2018 Dec 17. PMID 30562941, Free PMC Article
    3. ATG5 is required for B cell polarization and presentation of particulate antigens. Arbogast F, et al. Autophagy, 2019 Feb. PMID 30196744, Free PMC Article
    4. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein serine/threonine phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of circadian rhythm ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of PTW/PP1 phosphatase complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    colocalizes_with chromosome, telomeric region ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein phosphatase 1 catalytic subunit gamma B
    Names
    Protein phosphatase 1C catalytic subunit
    Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
    predicted pseudogene 5601

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001370947.1 → NP_001357876.1  protein phosphatase 1 catalytic subunit gamma B

      Status: VALIDATED

      Source sequence(s)
      AC164158
      UniProtKB/TrEMBL
      Q3U7K1
      Related
      ENSMUST00000207161.2
      Conserved Domains (1) summary
      cd07414
      Location:8 → 298
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      119339133..119341467
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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