U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    LOC4326547 hexokinase-6-like [ Oryza sativa Japonica Group (Japanese rice) ]

    Gene ID: 4326547, updated on 3-Apr-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    LOC4326547
    Gene description
    hexokinase-6-like
    Locus tag
    OSNPB_010742500
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Oryza sativa Japonica Group
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa
    Also known as
    HXK2; HXK6
    Expression
    Broad expression in flowers (RPKM 123.5), flower buds (RPKM 115.1) and 5 other tissues See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    102 current IRGSP-1.0 (GCF_001433935.1) 1 NC_029256.1 (31009687..31013954, complement)

    Chromosome 1 - NC_029256.1Genomic Context describing neighboring genes Neighboring gene elongation factor 2 Neighboring gene probable 3-hydroxyisobutyrate dehydrogenase-like 1, mitochondrial Neighboring gene receptor-like protein kinase HSL1 Neighboring gene uncharacterized LOC107276483 Neighboring gene protein IQ-DOMAIN 14

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_029256.1 Chromosome 1 Reference IRGSP-1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Transcriptome profiling of various organs at different developmental stages in rice
    • Description: Transcriptom profiling in flower buds, flowers, flag leaves and roots sampled before flowering and after flowering, milk grains and mature seeds
    • BioProject: PRJNA243371
    • Publication: PMID 26387578
    • Analysis date: Fri Dec 15 20:02:59 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Crystal structures of rice hexokinase 6 with a series of substrates shed light on its enzymatic mechanism. He C, et al. Biochem Biophys Res Commun, 2019 Aug 6. PMID 31176485
    2. Pentatricopeptide-repeat family protein RF6 functions with hexokinase 6 to rescue rice cytoplasmic male sterility. Huang W, et al. Proc Natl Acad Sci U S A, 2015 Dec 1. PMID 26578814, Free PMC Article
    3. Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Cho JI, et al. Planta, 2006 Aug. PMID 16552590
    4. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Rice Full-Length cDNA Consortium, et al. Science, 2003 Jul 18. PMID 12869764

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. in a conformational study of rice hexokinase 6, residues Gly112, Thr261, Gly262, and Gly450 are essential to the binding between ADP-PO4 and OsHXK6 by a series of single mutations and enzymatic assays
      Title: Crystal structures of rice hexokinase 6 with a series of substrates shed light on its enzymatic mechanism.
    2. Together these results reveal a novel mechanism for CMS restoration by which RF6 functions with OsHXK6 to restore HL-CMS fertility.
      Title: Pentatricopeptide-repeat family protein RF6 functions with hexokinase 6 to rescue rice cytoplasmic male sterility.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fructokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glucokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glucose binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables mannokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glucose 6-phosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glycolytic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular glucose homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    hexokinase-6
    Names
    Hexokinase-2
    LOC_Os01g53930
    P0439E07.19
    hexokinase 2
    putative hexokinase
    XP_015618116.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398030.1 → NP_001384959.1  hexokinase-6

      Status: VALIDATED

      Source sequence(s)
      AY884165, CI566868, CI593021
      UniProtKB/Swiss-Prot
      Q0JJF0, Q8LQ68
      UniProtKB/TrEMBL
      A2WUX9
      Conserved Domains (1) summary
      PLN02405
      Location:49 → 506
      PLN02405; hexokinase

    RefSeqs of Annotated Genomes: Oryza sativa Japonica Group Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference IRGSP-1.0 Primary Assembly

    Genomic

    1. NC_029256.1 Reference IRGSP-1.0 Primary Assembly

      Range
      31009687..31013954 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015762630.1 → XP_015618116.1  hexokinase-6

      UniProtKB/Swiss-Prot
      Q8LQ68
      Conserved Domains (1) summary
      PLN02405
      Location:49 → 506
      PLN02405; hexokinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LQ68.1 GenPept UniProtKB/Swiss-Prot:Q8LQ68

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Miscellaneous