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    CASS4 Cas scaffolding protein family member 4 [ Gallus gallus (chicken) ]

    Gene ID: 419330, updated on 11-Apr-2024

    Summary

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    Official Symbol
    CASS4provided by CGNC
    Official Full Name
    Cas scaffolding protein family member 4provided by CGNC
    Primary source
    CGNC:5856
    See related
    Ensembl:ENSGALG00010016671
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    C20orf32
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 20
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 20 NC_052551.1 (12332797..12351385, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 20 NC_052592.1 (12119614..12138247, complement)

    Chromosome 20 - NC_052551.1Genomic Context describing neighboring genes Neighboring gene transcription factor AP-2 gamma Neighboring gene uncharacterized LOC121107352 Neighboring gene replication termination factor 2 domain containing 1 Neighboring gene glucosaminyl (N-acetyl) transferase family member 7 Neighboring gene cleavage stimulation factor subunit 1 Neighboring gene aurora kinase B Neighboring gene family with sequence similarity 210 member B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cas scaffolding protein family member 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001389548.2 → NP_001376477.2  cas scaffolding protein family member 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000328
      UniProtKB/TrEMBL
      A0A8V0YWZ9, A0A8V0Z400
      Related
      ENSGALP00010023301.1, ENSGALT00010040193.1
      Conserved Domains (3) summary
      cd11551
      Location:457 → 615
      Serine_rich_CASS4; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
      cd11568
      Location:712 → 834
      FAT-like_CASS4_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
      cd12000
      Location:6 → 62
      SH3_CASS4; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4

    2. NM_001396849.1 → NP_001383778.1  cas scaffolding protein family member 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000328
      UniProtKB/TrEMBL
      A0A8V0YWZ9, A0A8V0YXE2
      Related
      ENSGALP00010023304.1, ENSGALT00010040196.1
      Conserved Domains (3) summary
      cd11551
      Location:461 → 619
      Serine_rich_CASS4; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
      cd11568
      Location:716 → 838
      FAT-like_CASS4_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
      cd12000
      Location:10 → 66
      SH3_CASS4; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4

    3. NM_001396850.1 → NP_001383779.1  cas scaffolding protein family member 4 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000328
      UniProtKB/TrEMBL
      A0A8V0YWZ9
      Conserved Domains (3) summary
      cd11551
      Location:461 → 619
      Serine_rich_CASS4; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
      cd11568
      Location:696 → 818
      FAT-like_CASS4_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
      cd12000
      Location:10 → 66
      SH3_CASS4; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4

    4. NM_001396851.1 → NP_001383780.1  cas scaffolding protein family member 4 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000328
      UniProtKB/TrEMBL
      A0A8V0YWZ9
      Related
      ENSGALP00010023300.1, ENSGALT00010040192.1
      Conserved Domains (3) summary
      cd11551
      Location:457 → 615
      Serine_rich_CASS4; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
      cd11568
      Location:692 → 814
      FAT-like_CASS4_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
      cd12000
      Location:6 → 62
      SH3_CASS4; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052551.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      12332797..12351385 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040650736.2 → XP_040506670.1  cas scaffolding protein family member 4 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YWZ9
      Conserved Domains (2) summary
      cd11551
      Location:351 → 509
      Serine_rich_CASS4; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
      cd11568
      Location:606 → 728
      FAT-like_CASS4_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module

    2. XM_046902885.1 → XP_046758841.1  cas scaffolding protein family member 4 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Z400

    3. XM_040650732.2 → XP_040506666.1  cas scaffolding protein family member 4 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YWZ9
      Conserved Domains (3) summary
      cd11551
      Location:478 → 636
      Serine_rich_CASS4; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
      cd11568
      Location:713 → 835
      FAT-like_CASS4_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
      cd12000
      Location:27 → 83
      SH3_CASS4; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4

    4. XM_040650730.2 → XP_040506664.1  cas scaffolding protein family member 4 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YWZ9
      Conserved Domains (3) summary
      cd11551
      Location:478 → 636
      Serine_rich_CASS4; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
      cd11568
      Location:733 → 855
      FAT-like_CASS4_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module
      cd12000
      Location:27 → 83
      SH3_CASS4; Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052592.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      12119614..12138247 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046930834.1 → XP_046786790.1  cas scaffolding protein family member 4 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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