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    DTX2 deltex E3 ubiquitin ligase 2 [ Gallus gallus (chicken) ]

    Gene ID: 417515, updated on 5-Mar-2024

    Summary

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    Symbol
    DTX2provided by CGNC
    Full Name
    deltex E3 ubiquitin ligase 2provided by CGNC
    Primary source
    CGNC:1346
    See related
    Ensembl:ENSGALG00010029192
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See DTX2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 19 NC_052550.1 (4668813..4695084, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 19 NC_052591.1 (4397018..4423226, complement)

    Chromosome 19 - NC_052550.1Genomic Context describing neighboring genes Neighboring gene uroplakin 3B-like Neighboring gene uroplakin 3B Neighboring gene uncharacterized LOC121107190 Neighboring gene PHD finger protein 7-like Neighboring gene scavenger receptor cysteine rich family member with 4 domains

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    probable E3 ubiquitin-protein ligase DTX2
    Names
    deltex 2, E3 ubiquitin ligase
    deltex homolog 2
    XP_015151492.2
    XP_015151493.2
    XP_015151494.2
    XP_015151495.2
    XP_040543057.1
    XP_040543058.1
    XP_040543059.1
    XP_040543060.1
    XP_046758527.1
    XP_046786182.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052550.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      4668813..4695084 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015296009.4 → XP_015151495.2  probable E3 ubiquitin-protein ligase DTX2 isoform X4

      UniProtKB/TrEMBL
      E1BWT2
      Related
      ENSGALP00010043240.1, ENSGALT00010070549.1
      Conserved Domains (3) summary
      cd09633
      Location:415 → 547
      Deltex_C; Domain found at the C-terminus of deltex-like
      pfam02825
      Location:122 → 187
      WWE; WWE domain
      cd16672
      Location:345 → 416
      RING-H2_DTX2; RING finger, H2 subclass, found in E3 ubiquitin-protein ligase Deltex2 (DTX2) and similar proteins

    2. XM_015296008.4 → XP_015151494.2  probable E3 ubiquitin-protein ligase DTX2 isoform X3

      UniProtKB/TrEMBL
      A0A3Q2U199
      Related
      ENSGALP00010043237.1, ENSGALT00010070546.1
      Conserved Domains (3) summary
      cd09633
      Location:430 → 562
      Deltex_C; Domain found at the C-terminus of deltex-like
      pfam02825
      Location:122 → 187
      WWE; WWE domain
      cd16672
      Location:360 → 431
      RING-H2_DTX2; RING finger, H2 subclass, found in E3 ubiquitin-protein ligase Deltex2 (DTX2) and similar proteins

    3. XM_015296007.4 → XP_015151493.2  probable E3 ubiquitin-protein ligase DTX2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q3A808
      Related
      ENSGALP00010043239.1, ENSGALT00010070548.1
      Conserved Domains (3) summary
      cd09633
      Location:459 → 591
      Deltex_C; Domain found at the C-terminus of deltex-like
      pfam02825
      Location:122 → 187
      WWE; WWE domain
      cd16672
      Location:389 → 460
      RING-H2_DTX2; RING finger, H2 subclass, found in E3 ubiquitin-protein ligase Deltex2 (DTX2) and similar proteins

    4. XM_015296006.4 → XP_015151492.2  probable E3 ubiquitin-protein ligase DTX2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q2TTJ2
      Related
      ENSGALP00010043238.1, ENSGALT00010070547.1
      Conserved Domains (3) summary
      cd09633
      Location:474 → 606
      Deltex_C; Domain found at the C-terminus of deltex-like
      pfam02825
      Location:122 → 187
      WWE; WWE domain
      cd16672
      Location:404 → 475
      RING-H2_DTX2; RING finger, H2 subclass, found in E3 ubiquitin-protein ligase Deltex2 (DTX2) and similar proteins

    5. XM_046902571.1 → XP_046758527.1  probable E3 ubiquitin-protein ligase DTX2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q2TTJ2

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052591.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      4397018..4423226 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040687126.2 → XP_040543060.1  probable E3 ubiquitin-protein ligase DTX2 isoform X4

      Conserved Domains (3) summary
      smart00678
      Location:31 → 114
      WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
      cd09633
      Location:415 → 547
      Deltex_C; Domain found at the C-terminus of deltex-like
      cd16672
      Location:345 → 416
      RING-H2_DTX2; RING finger, H2 subclass, found in E3 ubiquitin-protein ligase Deltex2 (DTX2) and similar proteins

    2. XM_040687125.2 → XP_040543059.1  probable E3 ubiquitin-protein ligase DTX2 isoform X3

      Conserved Domains (3) summary
      smart00678
      Location:31 → 114
      WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
      cd09633
      Location:430 → 562
      Deltex_C; Domain found at the C-terminus of deltex-like
      cd16672
      Location:360 → 431
      RING-H2_DTX2; RING finger, H2 subclass, found in E3 ubiquitin-protein ligase Deltex2 (DTX2) and similar proteins

    3. XM_040687124.2 → XP_040543058.1  probable E3 ubiquitin-protein ligase DTX2 isoform X2

      Conserved Domains (3) summary
      smart00678
      Location:31 → 114
      WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
      cd09633
      Location:459 → 591
      Deltex_C; Domain found at the C-terminus of deltex-like
      cd16672
      Location:389 → 460
      RING-H2_DTX2; RING finger, H2 subclass, found in E3 ubiquitin-protein ligase Deltex2 (DTX2) and similar proteins

    4. XM_040687123.2 → XP_040543057.1  probable E3 ubiquitin-protein ligase DTX2 isoform X1

      Conserved Domains (3) summary
      smart00678
      Location:31 → 114
      WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
      cd09633
      Location:474 → 606
      Deltex_C; Domain found at the C-terminus of deltex-like
      cd16672
      Location:404 → 475
      RING-H2_DTX2; RING finger, H2 subclass, found in E3 ubiquitin-protein ligase Deltex2 (DTX2) and similar proteins

    5. XM_046930226.1 → XP_046786182.1  probable E3 ubiquitin-protein ligase DTX2 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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