ndufa4b NDUFA4 mitochondrial complex associated b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ndufa4bprovided by ZNC
Official Full Name: NDUFA4 mitochondrial complex associated bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1962
See related: Ensembl:ENSDARG00000056108 AllianceGenome:ZFIN:ZDB-GENE-040426-1962
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ndufa4; zgc:73405
Summary: Predicted to contribute to cytochrome-c oxidase activity. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be integral component of membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Is expressed in several structures, including gut; musculature system; nervous system; neural tube; and pericardial region. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human NDUFA4 (NDUFA4 mitochondrial complex associated). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 12

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (9880814..9884326)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (9842971..9846483)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
part_of mitochondrial respiratory chain complex IV	IBA Inferred from Biological aspect of Ancestor more info
part_of mitochondrial respiratory chain complex IV	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in respirasome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cytochrome c oxidase subunit NDUFA4

Names: NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; NADH:ubiquinone oxidoreductase subunit A4

NP_998190.1

EC 1.6.99.3

EC 7.1.1.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.