DBT dihydrolipoamide branched chain transacylase E2 [Gallus gallus (chicken)] - Gene

Summary

Symbol: DBTprovided by CGNC
Full Name: dihydrolipoamide branched chain transacylase E2provided by CGNC
Primary source: CGNC:3929
See related: Ensembl:ENSGALG00010023826
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 8

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	8	NC_052539.1 (11638958..11651985)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	8	NC_052580.1 (11646813..11659839)

Chromosome 8 - NC_052539.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables acetyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables lipoic acid binding	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

Names: mitochondrial branched-chain alpha-keto acid dihydrolipoyl acyltransferase

NP_989987.1

EC 2.3.1.168

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204656.2 → NP_989987.1 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial precursor

See identical proteins and their annotated locations for NP_989987.1

Status: PROVISIONAL

Source sequence(s)

JAENSK010000239

UniProtKB/TrEMBL

A0A8V0ZY80, Q98UJ6

Related

ENSGALP00010035287.1, ENSGALT00010058117.1

Conserved Domains (4) summary

cd06849
Location:65 → 138

lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...

PLN02528
Location:67 → 493

PLN02528; 2-oxoisovalerate dehydrogenase E2 component

pfam00198
Location:278 → 490

2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)

pfam02817
Location:174 → 207

E3_binding; e3 binding domain