Flo1 Flotillin 1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Flo1provided by FlyBase
Official Full Name: Flotillin 1provided by FlyBase
Primary source: FLYBASE:FBgn0024754
Locus tag: Dmel_CG8200
See related: AllianceGenome:FB:FBgn0024754
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG8200; CK02126; dFlot1; Dmel\CG8200; flo; Flo; Flo-1; flo1; FLO1; Flot1; flotillin; Flo[Dm]; FLO[Dm]; FLO[Dm]-1; reggie-2
Summary: Predicted to be involved in several processes, including positive regulation of cell-cell adhesion mediated by cadherin; protein kinase C signaling; and regulation of endocytosis. Located in cytoplasm. Is expressed in several structures, including extended germ band embryo; head; presumptive embryonic/larval system; sensory nervous system primordium; and ventral midline of embryo. Orthologous to human FLOT1 (flotillin 1). [provided by Alliance of Genome Resources, Apr 2022]
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (15566271..15569404, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (11453776..11456909, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables protease binding	IBA Inferred from Biological aspect of Ancestor more info
enables structural molecule activity	NAS Non-traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of cell junction assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of cell-cell adhesion mediated by cadherin	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of endocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein kinase C signaling	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein localization to plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of receptor internalization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
is_active_in cytoplasmic vesicle	IBA Inferred from Biological aspect of Ancestor more info
part_of flotillin complex	IBA Inferred from Biological aspect of Ancestor more info
part_of flotillin complex	NAS Non-traceable Author Statement more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

Names: CG8200-PA; CG8200-PB; Flo1-PA; Flo1-PB; Flotillin-1; Flotillin1; flotillin; reggie2

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The following sections contain reference sequences that belong to a specific genome build. Explain