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    Zxdc ZXD family zinc finger C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362399, updated on 11-Apr-2024

    Summary

    Official Symbol
    Zxdcprovided by RGD
    Official Full Name
    ZXD family zinc finger Cprovided by RGD
    Primary source
    RGD:1561296
    See related
    Ensembl:ENSRNOG00000025818 AllianceGenome:RGD:1561296
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1561296
    Summary
    Predicted to enable C2H2 zinc finger domain binding activity; LRR domain binding activity; and transcription coactivator activity. Predicted to be involved in positive regulation of transcription, DNA-templated and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZXDC (ZXD family zinc finger C). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 85.9), Lung (RPKM 70.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    Location:
    4q34
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (124439560..124471694)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (122882389..122914486)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (122282119..122314251)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene carbohydrate sulfotransferase 13 Neighboring gene urocanate hydratase 1 Neighboring gene uncharacterized LOC134486812 Neighboring gene cilia and flagella associated protein 100 Neighboring gene KLF transcription factor 15

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables C2H2 zinc finger domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables LRR domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ZXD family zinc finger C; zinc finger protein ZXDC

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      124439560..124471694
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002729395.7XP_002729441.4  zinc finger protein ZXDC

      UniProtKB/TrEMBL
      A0A8I5ZSE5, D3ZYP0
      Related
      ENSRNOP00000032693.4
      Conserved Domains (4) summary
      COG5048
      Location:414692
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:356375
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:398424
      zf-H2C2_2; Zinc-finger double domain
      pfam15909
      Location:263340
      zf-C2H2_8; C2H2-type zinc ribbon