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    CG3149 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31489, updated on 4-Apr-2024

    Summary

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    Official Symbol
    CG3149provided by FlyBase
    Primary source
    FLYBASE:FBgn0027564
    Locus tag
    Dmel_CG3149
    See related
    AllianceGenome:FB:FBgn0027564
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH08388; Dmel\CG3149
    Summary
    Predicted to be involved in glycolipid translocation. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation In. Orthologous to human RFT1 (RFT1 homolog). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See CG3149 in Genome Data Viewer
    Location:
    5A13-5A14; 1-12 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5692945..5695205, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5586978..5589238, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Post-GPI attachment to proteins 1 Neighboring gene antisense RNA:CR45525 Neighboring gene crossveinless Neighboring gene long non-coding RNA:CR42794 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif B Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. crossveinless defines a new family of Twisted-gastrulation-like modulators of bone morphogenetic protein signalling. Vilmos P, et al. EMBO Rep, 2005 Mar. PMID 15711536, Free PMC Article
    2. The crossveinless gene encodes a new member of the Twisted gastrulation family of BMP-binding proteins which, with Short gastrulation, promotes BMP signaling in the crossveins of the Drosophila wing. Shimmi O, et al. Dev Biol, 2005 Jun 1. PMID 15936330
    3. Genomic organization of gypsy chromatin insulators in Drosophila melanogaster. Ramos E, et al. Genetics, 2006 Apr. PMID 16452134, Free PMC Article
    4. A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila. Okamoto N, et al. Dev Cell, 2018 Nov 5. PMID 30293839, Free PMC Article
    5. A Genetic Screen for Genes That Impact Peroxisomes in Drosophila Identifies Candidate Genes for Human Disease. Graves HK, et al. G3 (Bethesda), 2020 Jan 7. PMID 31767637, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in dolichol-linked oligosaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glycolipid translocation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3149-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      5692945..5695205 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132018.3 → NP_572246.1  uncharacterized protein Dmel_CG3149 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572246.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9Y123
      Related
      FBpp0070811
      Conserved Domains (1) summary
      pfam04506
      Location:8 → 547
      Rft-1; Rft protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9Y123.1 Q9Y123

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
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    Research Materials
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