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    Cfap54 cilia and flagella associated protein 54 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314740, updated on 11-Apr-2024

    Summary

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    Symbol
    Cfap54provided by RGD
    Full Name
    cilia and flagella associated protein 54provided by RGD
    Primary source
    RGD:1565866
    See related
    Ensembl:ENSRNOG00000024494 AllianceGenome:RGD:1565866
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565866; AABR07056633.1
    Expression
    Biased expression in Testes (RPKM 53.0), Lung (RPKM 37.3) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    7q13
    Exon count:
    68
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (29203143..29489551, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (27316498..27601630, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (33623692..33916849, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120093847 Neighboring gene small nucleolar RNA SNORA79 Neighboring gene NEDD1 gamma-tubulin ring complex targeting factor Neighboring gene uncharacterized LOC120093552 Neighboring gene uncharacterized LOC134479658 Neighboring gene cyclin-dependent kinase 17 Neighboring gene uncharacterized LOC102548950 Neighboring gene ETS transcription factor ELK3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. CFAP54 is required for proper ciliary motility and assembly of the central pair apparatus in mice. McKenzie CW, et al. Mol Biol Cell, 2015 Sep 15. PMID 26224312, Free PMC Article
    2. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within cerebrospinal fluid circulation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cilium movement involved in cell motility ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within establishment of localization in cell ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within mucociliary clearance ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within sperm flagellum assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular region ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    cilia- and flagella-associated protein 54; similar to FLJ44112 protein
    Names
    cilia and flagella associated 54

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      29203143..29489551 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039080085.2 → XP_038936013.1  cilia- and flagella-associated protein 54 isoform X5

      UniProtKB/TrEMBL
      A0A8I6AZY6, F1M063
      Related
      ENSRNOP00000094294.1
      Conserved Domains (1) summary
      pfam14858
      Location:104 → 596
      DUF4486; Domain of unknown function (DUF4486)

    2. XM_039080086.2 → XP_038936014.1  cilia- and flagella-associated protein 54 isoform X6

      UniProtKB/TrEMBL
      F1M063
      Conserved Domains (1) summary
      pfam14858
      Location:104 → 528
      DUF4486; Domain of unknown function (DUF4486)

    3. XM_039080083.2 → XP_038936011.1  cilia- and flagella-associated protein 54 isoform X2

      UniProtKB/TrEMBL
      F1M063
      Conserved Domains (1) summary
      pfam14858
      Location:104 → 644
      DUF4486; Domain of unknown function (DUF4486)

    4. XM_039080084.2 → XP_038936012.1  cilia- and flagella-associated protein 54 isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZKH9, F1M063
      Related
      ENSRNOP00000078236.1
      Conserved Domains (1) summary
      pfam14858
      Location:104 → 644
      DUF4486; Domain of unknown function (DUF4486)

    5. XM_063264407.1 → XP_063120477.1  cilia- and flagella-associated protein 54 isoform X4

      UniProtKB/TrEMBL
      A0A8I5YB90

    6. XM_039080082.2 → XP_038936010.1  cilia- and flagella-associated protein 54 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZLU8, F1M063
      Related
      ENSRNOP00000078736.1
      Conserved Domains (1) summary
      pfam14858
      Location:104 → 644
      DUF4486; Domain of unknown function (DUF4486)

    7. XM_039080088.2 → XP_038936016.1  cilia- and flagella-associated protein 54 isoform X7

      Conserved Domains (1) summary
      pfam14858
      Location:104 → 644
      DUF4486; Domain of unknown function (DUF4486)

    8. XM_039080089.2 → XP_038936017.1  cilia- and flagella-associated protein 54 isoform X8

      Conserved Domains (1) summary
      pfam14858
      Location:104 → 644
      DUF4486; Domain of unknown function (DUF4486)

    RNA

    1. XR_005486835.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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    Other Literature Sources
    Molecular Biology Databases
    Miscellaneous