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    Zfp711 zinc finger protein 711 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 302327, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Zfp711provided by RGD
    Official Full Name
    zinc finger protein 711provided by RGD
    Primary source
    RGD:1562768
    See related
    Ensembl:ENSRNOG00000022391 AllianceGenome:RGD:1562768
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf711; RGD1562768
    Summary
    Predicted to enable chromatin insulator sequence binding activity and sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription, DNA-templated and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in chromosome. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 97. Orthologous to human ZNF711 (zinc finger protein 711). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Testes (RPKM 43.2), Brain (RPKM 34.9) and 5 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    Xq31
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (81838483..81871767)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (77646300..77679398)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (84062363..84095888)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation elongation factor 1 alpha 1, pseudogene 18 Neighboring gene RIKEN cDNA 2010106E10 gene like Neighboring gene POF1B, actin binding protein Neighboring gene replication factor C subunit 4, pseudogene 1 Neighboring gene uncharacterized LOC134484037

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation. Kleine-Kohlbrecher D, et al. Mol Cell, 2010 Apr 23. PMID 20346720, Free PMC Article
    2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables chromatin insulator sequence binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in chromosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 711

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001401122.1 → NP_001388051.1  zinc finger protein 711

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A0A8I5ZQU3
      Related
      ENSRNOP00000080686.1, ENSRNOT00000095292.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      81838483..81871767
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017602345.3 → XP_017457834.1  zinc finger protein 711 isoform X1

      UniProtKB/TrEMBL
      A6IVA2, D3ZHB2
      Conserved Domains (3) summary
      COG5048
      Location:425 → 803
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:551 → 571
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04704
      Location:65 → 412
      Zfx_Zfy_act; Zfx / Zfy transcription activation region

    2. XM_063279891.1 → XP_063135961.1  zinc finger protein 711 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZQU3

    3. XM_039100220.2 → XP_038956148.1  zinc finger protein 711 isoform X1

      UniProtKB/TrEMBL
      A6IVA2, D3ZHB2
      Conserved Domains (3) summary
      COG5048
      Location:425 → 803
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:551 → 571
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04704
      Location:65 → 412
      Zfx_Zfy_act; Zfx / Zfy transcription activation region

    4. XM_002730265.6 → XP_002730311.1  zinc finger protein 711 isoform X1

      See identical proteins and their annotated locations for XP_002730311.1

      UniProtKB/TrEMBL
      A6IVA2, D3ZHB2
      Related
      ENSRNOP00000041511.3
      Conserved Domains (3) summary
      COG5048
      Location:425 → 803
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:551 → 571
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04704
      Location:65 → 412
      Zfx_Zfy_act; Zfx / Zfy transcription activation region
    Nucleotide Protein Strain
    Heading Accession and Version

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